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Kent S. Gates, Ph.D.

Affiliations: 
1993- Chemistry University of Missouri-Columbia, Columbia, MO 
Area:
Medicinal Chemistry
Website:
http://faculty.missouri.edu/~gatesk/index.html
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"Kent Gates"
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Publications

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Price NE, Gates KS. (2024) Novel Processes Associated with the Repair of Interstrand Cross-Links Derived from Abasic Sites in Duplex DNA: Roles for the Base Excision Repair Glycosylase NEIL3 and the SRAP Protein HMCES. Chemical Research in Toxicology
Gomina A, Islam T, Shim G, et al. (2024) Formation and Properties of DNA Adducts Generated by Reactions of Abasic Sites with 1,2-Aminothiols Including Cysteamine, Cysteine Methyl Ester, and Peptides Containing -Terminal Cysteine Residues. Chemical Research in Toxicology
Yin J, Gates KS, Wang Y. (2022) -Methyl--nitrosourea Induced 3'-Glutathionylated DNA-Cleavage Products in Mammalian Cells. Analytical Chemistry. 94: 15595-15603
Amin SBM, Islam T, Price NE, et al. (2022) Effects of Local Sequence, Reaction Conditions, and Various Additives on the Formation and Stability of Interstrand Cross-Links Derived from the Reaction of an Abasic Site with an Adenine Residue in Duplex DNA. Acs Omega. 7: 36888-36901
Jha JS, Yin J, Haldar T, et al. (2022) Reconsidering the Chemical Nature of Strand Breaks Derived from Abasic Sites in Cellular DNA: Evidence for 3'-Glutathionylation. Journal of the American Chemical Society
Haldar T, Jha JS, Yang Z, et al. (2022) Unexpected Complexity in the Products Arising from NaOH-, Heat-, Amine-, and Glycosylase-Induced Strand Cleavage at an Abasic Site in DNA. Chemical Research in Toxicology. 35: 218-232
Jha JS, Nel C, Haldar T, et al. (2022) Products Generated by Amine-Catalyzed Strand Cleavage at Apurinic/Apyrimidinic Sites in DNA: New Insights from a Biomimetic Nucleoside Model System. Chemical Research in Toxicology. 35: 203-217
Housh K, Gates KS. (2021) Synthesis of DNA Duplexes Containing Site-Specific Interstrand Cross-Links via Sequential Reductive Amination Reactions Involving Diamine Linkers and Abasic Sites on Complementary Oligodeoxynucleotides. Chemical Research in Toxicology. 34: 2384-2391
Housh K, Jha JS, Yang Z, et al. (2021) Formation and Repair of an Interstrand DNA Cross-Link Arising from a Common Endogenous Lesion. Journal of the American Chemical Society
Housh K, Jha JS, Haldar T, et al. (2020) Formation and repair of unavoidable, endogenous interstrand cross-links in cellular DNA. Dna Repair. 98: 103029
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