Maria Lokshin, Ph.D.

Affiliations: 
Columbia University, New York, NY 
Area:
p53 tumour suppressor protein
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"Maria Lokshin"
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Parents

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Carol L. Prives grad student 2007 Columbia
 (Differential activity and regulation of family members p53 and p73.)
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Publications

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Karni-Schmidt O, Lokshin M, Prives C. (2016) The Roles of MDM2 and MDMX in Cancer. Annual Review of Pathology
Poyurovsky MV, Katz C, Laptenko O, et al. (2011) Erratum: The C terminus of p53 binds the N-terminal domain of MDM2 Nature Structural & Molecular Biology. 18: 516-516
Poyurovsky MV, Katz C, Laptenko O, et al. (2010) The C terminus of p53 binds the N-terminal domain of MDM2. Nature Structural & Molecular Biology. 17: 982-9
Suzuki S, Tanaka T, Poyurovsky MV, et al. (2010) Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species. Proceedings of the National Academy of Sciences of the United States of America. 107: 7461-6
Reid LJ, Shakya R, Modi AP, et al. (2008) E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks. Proceedings of the National Academy of Sciences of the United States of America. 105: 20876-81
Lokshin M, Li Y, Gaiddon C, et al. (2007) p53 and p73 display common and distinct requirements for sequence specific binding to DNA. Nucleic Acids Research. 35: 340-52
Lokshin M, Tanaka T, Prives C. (2005) Transcriptional regulation by p53 and p73. Cold Spring Harbor Symposia On Quantitative Biology. 70: 121-8
Gaiddon C, Lokshin M, Gross I, et al. (2003) Cyclin-dependent kinases phosphorylate p73 at threonine 86 in a cell cycle-dependent manner and negatively regulate p73. The Journal of Biological Chemistry. 278: 27421-31
Gaiddon C, Lokshin M, Ahn J, et al. (2001) A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain. Molecular and Cellular Biology. 21: 1874-87
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