Sunil Laxman, Ph.D.

Affiliations: 
 
Area:
metabolism, signaling, amino acids, biochemical networks
Website:
sunillaxmanlab.weebly.com/
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"Sunil Laxman"
Mean distance: 11.05
 
SNBCP

Parents

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Joseph A. Beavo grad student 2006 University of Washington
 (cAMP signaling and regulation by phosphodiesterases in trypanosomes.)
Steven L. McKnight post-doc 2007-2009 The University of Texas Southwestern Medical Center
Benjamin P. Tu post-doc 2009-2014 The University of Texas Southwestern Medical Center
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Publications

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Walvekar AS, Kadamur G, Sreedharan S, et al. (2020) Methylated PP2A stabilizes Gcn4 to enable a methionine-induced anabolic program. The Journal of Biological Chemistry. 295: 18390-18405
Srinivasan R, Walvekar AS, Rashida Z, et al. (2020) Genome-scale reconstruction of Gcn4/ATF4 networks driving a growth program. Plos Genetics. 16: e1009252
Walvekar AS, Kadamur G, Sreedharan S, et al. (2020) Methylated PP2A stabilizes Gcn4 to enable a methionine-induced anabolic program. The Journal of Biological Chemistry
Bhatia M, Thakur J, Suyal S, et al. (2020) Allosteric inhibition of MTHFR prevents futile SAM cycling and maintains nucleotide pools in one carbon metabolism. The Journal of Biological Chemistry
Varahan S, Sinha V, Walvekar A, et al. (2020) Resource plasticity-driven carbon-nitrogen budgeting enables specialization and division of labor in a clonal community. Elife. 9
Bruhn C, Ajazi A, Ferrari E, et al. (2020) The Rad53-Spt21 and Tel1 axes couple glucose tolerance to histone dosage and subtelomeric silencing. Nature Communications. 11: 4154
Walvekar AS, Laxman S. (2019) Methionine at the Heart of Anabolism and Signaling: Perspectives From Budding Yeast. Frontiers in Microbiology. 10: 2624
Gupta R, Laxman S. (2019) tRNA wobble-uridine modifications as amino acid sensors and regulators of cellular metabolic state. Current Genetics
Shaw E, Talwadekar M, Rashida Z, et al. (2019) Anabolic SIRT4 exerts retrograde control over TORC1 signalling by glutamine sparing in the mitochondria. Molecular and Cellular Biology
Vengayil V, Rashida Z, Laxman S. (2019) The E3 ubiquitin ligase Pib1 regulates effective gluconeogenic shutdown upon glucose availability. The Journal of Biological Chemistry
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