Wenbo Zhou, Ph.D.

lipoxygenase

Theodore R. Holman	grad student	2006	UC Santa Cruz
(Factors that regulate aggregation, fibrillation of alpha-synuclein and its relation to Parkinson's disease.)

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Zhou W, Long C, Reaney SH, et al. (2010) Methionine oxidation stabilizes non-toxic oligomers of alpha-synuclein through strengthening the auto-inhibitory intra-molecular long-range interactions. Biochimica Et Biophysica Acta. 1802: 322-30
Zhou W, Long C, Fink AL, et al. (2010) 3, 4-Dihydroxyphenylacetic Acid (DOPAC) Impairs α-Synuclein Interaction with Lipids The Open Proteomics Journal. 3: 1-7
Zhou W, Gallagher A, Hong DP, et al. (2009) At low concentrations, 3,4-dihydroxyphenylacetic acid (DOPAC) binds non-covalently to alpha-synuclein and prevents its fibrillation. Journal of Molecular Biology. 388: 597-610
Zhou W, Zhu M, Wilson MA, et al. (2006) The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein. Journal of Molecular Biology. 356: 1036-48
Zhou W, Freed CR. (2004) Tyrosine-to-cysteine modification of human alpha-synuclein enhances protein aggregation and cellular toxicity. The Journal of Biological Chemistry. 279: 10128-35