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Jingyi Wang, Ph.D.

Affiliations: 
Chemistry University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Organic Chemistry, Enzymology, Bioorganic Chemistry
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"Jingyi Wang"
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Parents

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Nicole A. Horenstein grad student 2011 UF Gainesville
 (Using molecular tools to study the structure and functional states of the human alpha7 nicotinic acetylcholine receptor.)

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Publications

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Norleans J, Wang J, Kuryatov A, et al. (2019) Discovery of an intrasubunit nicotinic acetylcholine receptor binding site for the positive allosteric modulator Br-PBTC. The Journal of Biological Chemistry
Wang J, Lindstrom J. (2017) Orthosteric and Allosteric Potentiation of Heteromeric Neuronal Nicotinic Acetylcholine Receptors. British Journal of Pharmacology
Jain A, Kuryatov A, Wang J, et al. (2016) Unorthodox Acetylcholine Binding Sites Formed by α5 and β3 Accessory Subunits in α4β2* Nicotinic Acetylcholine Receptors. The Journal of Biological Chemistry
Wang J, Kuryatov A, Jin Z, et al. (2015) A Novel α2/α4 Subtype-Selective Positive Allosteric Modulator of Nicotinic Acetylcholine Receptors Acting From the C-tail of an α Subunit. The Journal of Biological Chemistry
Wang J, Kuryatov A, Sriram A, et al. (2015) An Accessory Agonist Binding Site Promotes Activation of α4β2* Nicotinic Acetylcholine Receptors. The Journal of Biological Chemistry. 290: 13907-18
Wang J, Kuryatov A, Lindstrom J. (2015) Expression of cloned α6* nicotinic acetylcholine receptors. Neuropharmacology. 96: 194-204
Ley CK, Kuryatov A, Wang J, et al. (2014) Efficient expression of functional (α6β2)2β3 AChRs in Xenopus oocytes from free subunits using slightly modified α6 subunits. Plos One. 9: e103244
Jin Z, Khan P, Shin Y, et al. (2014) Synthesis and activity of substituted heteroaromatics as positive allosteric modulators for α4β2α5 nicotinic acetylcholine receptors. Bioorganic & Medicinal Chemistry Letters. 24: 674-8
Wang J, Papke RL, Stokes C, et al. (2012) Potential state-selective hydrogen bond formation can modulate activation and desensitization of the α7 nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 287: 21957-69
Williams DK, Wang J, Papke RL. (2011) Investigation of the molecular mechanism of the α7 nicotinic acetylcholine receptor positive allosteric modulator PNU-120596 provides evidence for two distinct desensitized states. Molecular Pharmacology. 80: 1013-32
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