Zheng Xu, Ph.D.
Affiliations: | University of California, San Francisco, San Francisco, CA |
Area:
Signal transduction in lymphocytesGoogle:
"Zheng Xu"Mean distance: 10.8 | S | N | B | C | P |
Parents
Sign in to add mentor| Arthur Weiss | grad student | 2002 | UCSF | |
| (The function and regulation of protein and lipid phosphatases in T cell receptor signal transduction.) | ||||
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Publications
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| Li HF, Wu C, Chen T, et al. (2015) Construction and characterization of an anti-CD20 mAb nanocomb with exceptionally excellent lymphoma-suppressing activity. International Journal of Nanomedicine. 10: 4783-96 |
| Hermiston ML, Xu Z, Weiss A. (2003) CD45: a critical regulator of signaling thresholds in immune cells. Annual Review of Immunology. 21: 107-37 |
| Kane LP, Mollenauer MN, Xu Z, et al. (2002) Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription. Molecular and Cellular Biology. 22: 5962-74 |
| Xu Z, Weiss A. (2002) Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms. Nature Immunology. 3: 764-71 |
| Xu Z, Stokoe D, Kane LP, et al. (2002) The inducible expression of the tumor suppressor gene PTEN promotes apoptosis and decreases cell size by inhibiting the PI3K/Akt pathway in Jurkat T cells. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 13: 285-96 |
| Hermiston ML, Xu Z, Majeti R, et al. (2002) Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases. The Journal of Clinical Investigation. 109: 9-14 |
| Majeti R, Xu Z, Parslow TG, et al. (2000) An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity. Cell. 103: 1059-70 |