Aaron L. Lucius, Ph.D.

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 
Area:
DNA helises, SSB proteins, DNA repair
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"Aaron Lucius"
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Timothy M. Lohman grad student 2003 Washington University
 (Mechanism of Escherichia coli RecBCD helicase-catalyzed DNA unwinding and general methods for analysis using sequential N-step kinetic models.)
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Publications

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Foroutannejad S, Good LL, Lin C, et al. (2023) The cofactor-dependent folding mechanism of Drosophila cryptochrome revealed by single-molecule pulling experiments. Nature Communications. 14: 1057
Lin J, Shorter J, Lucius AL. (2022) AAA+ proteins: one motor, multiple ways to work. Biochemical Society Transactions
Scull NW, Lucius AL. (2020) Kinetic Analysis of AAA+ Translocases by Combined Fluorescence and Anisotropy Methods. Biophysical Journal. 119: 1335-1350
Lopez KE, Rizo AN, Tse E, et al. (2020) Conformational plasticity of the ClpAP AAA+ protease couples protein unfolding and proteolysis. Nature Structural & Molecular Biology
Lucius AL. (2020) Molecular Mechanisms of Enzyme Catalyzed Protein Unfolding and Translocation by Class 1 AAA+ Motor Biophysical Journal. 118: 319a
Scull CE, Clarke AM, Lucius AL, et al. (2019) Downstream sequence-dependent RNA cleavage and pausing by RNA polymerase I. The Journal of Biological Chemistry
Duran EC, Lucius AL. (2019) Examination of the nucleotide linked assembly mechanism of E. coli ClpA. Protein Science : a Publication of the Protein Society
Durie CL, Lin J, Scull NW, et al. (2019) Hsp104 and Potentiated Variants Can Operate as Distinct Nonprocessive Translocases. Biophysical Journal
Scull CE, Ingram ZM, Lucius AL, et al. (2019) A novel assay for RNA polymerase I transcription elongation sheds light on the evolutionary divergence of eukaryotic RNA polymerases. Biochemistry
Duran EC, Lucius AL. (2018) ATP hydrolysis inactivating Walker B mutation perturbs E. coli ClpA self-assembly energetics in the absence of nucleotide. Biophysical Chemistry. 242: 6-14
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