Joshua D. Sieber, Ph.D.

Affiliations: 
Boston College, Newton, MA, United States 
Area:
organic synthesis, methodology
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Parents

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James P. Morken grad student 2008 Boston College
 (The tandem catalytic asymmetric allene diboration/imine allylation and the asymmetric transition-metal-catalyzed conjugate allylation of activated enones.)

Children

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Samantha L Gargaro grad student VCU
Raphael K. Klake grad student 2018-2023 VCU
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Publications

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Collins S, Sieber JD. (2023) Development of regiodivergent asymmetric reductive coupling reactions of allenamides to access heteroatom-rich organic compounds. Chemical Communications (Cambridge, England). 59: 10087-10100
Klake RK, Sieber JD. (2023) Aminoalcohol Synthesis through Nonprecious Metal Catalysis: Enantioselective Cu-Catalyzed Reductive Coupling of Aldehydes and Allenamides. Organic Letters
Gargaro SL, Klake RK, Sieber JD. (2023) Asymmetric Access to Boryl-Substituted Vicinal Aminoalcohols through Cu-Catalyzed Reductive Coupling. Organic Letters
Collins S, Sieber JD. (2023) Studies Toward Improved Enantiocontrol in the Asymmetric Cu-Catalyzed Reductive Coupling of Ketones and Allenamides: 1,2-Aminoalcohol Synthesis. Organic Letters. 25: 1425-1430
Agrawal T, Perez-Morales KD, Cort JA, et al. (2022) Asymmetric Synthesis of Propargylic α-Stereogenic Tertiary Amines by Reductive Alkynylation of Tertiary Amides Using Ir/Cu Tandem Catalysis. The Journal of Organic Chemistry. 87: 6387-6392
Gopalsamuthiram V, Ho DB, Peck CL, et al. (2022) Development of a Practical Synthesis of the Fragment of OPC-167832. Acs Omega. 7: 7223-7228
Ho DB, Gargaro S, Klake RK, et al. (2021) Development of a Modified System to Provide Improved Diastereocontrol in the Linear-Selective Cu-Catalyzed Reductive Coupling of Ketones and Allenamides. The Journal of Organic Chemistry
Klake RK, Edwards MD, Sieber JD. (2021) Synthesis of 1,2-Aminoalcohols through Enantioselective Aminoallylation of Ketones by Cu-Catalyzed Reductive Coupling. Organic Letters
Agrawal T, Martin RT, Collins S, et al. (2021) Access to Chiral Diamine Derivatives through Stereoselective Cu-Catalyzed Reductive Coupling of Imines and Allenamides. The Journal of Organic Chemistry
Paymode DJ, Cardoso FSP, Agrawal T, et al. (2020) Expanding Access to Remdesivir via an Improved Pyrrolotriazine Synthesis: Supply Centered Synthesis. Organic Letters
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