Yang Xie, Ph.D.

Affiliations: 
Yale University, New Haven, CT 
Area:
Protein degradation, ubiquitin
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"Yang Xie"
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Mark W. Hochstrasser grad student 2009 Yale
 (Identification and characterization of a SUMO-targeted ubiquitin ligase (E3) complex in Saccharomyces cerevisiae.)
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Publications

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Hickey CM, Xie Y, Hochstrasser M. (2018) DNA Binding by the MATα2 Transcription Factor Controls its Access to Alternative Ubiquitin-modification Pathways. Molecular Biology of the Cell
Xie Y, Avello M, Schirle M, et al. (2013) Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation. The Journal of Biological Chemistry. 288: 2976-85
Ruffner H, Sprunger J, Charlat O, et al. (2012) R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5. Plos One. 7: e40976
Hao HX, Xie Y, Zhang Y, et al. (2012) ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner. Nature. 485: 195-200
Xie Y, Rubenstein EM, Matt T, et al. (2010) SUMO-independent in vivo activity of a SUMO-targeted ubiquitin ligase toward a short-lived transcription factor. Genes & Development. 24: 893-903
Xu P, Duong DM, Seyfried NT, et al. (2009) Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation. Cell. 137: 133-45
Xie Y, Kerscher O, Kroetz MB, et al. (2007) The yeast Hex3.Slx8 heterodimer is a ubiquitin ligase stimulated by substrate sumoylation. The Journal of Biological Chemistry. 282: 34176-84
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