Jeffrey R. Brender, Ph.D.
Affiliations: | University of Michigan, Ann Arbor, Ann Arbor, MI |
Area:
Structural Enzymology, Protein Processing and FoldingWebsite:
http://rams.biop.lsa.umich.edu/lab-members/jeffrey-brenderGoogle:
"Jeffrey Brender"Mean distance: 10.17 | S | N | B | C | P |
Parents
Sign in to add mentorAri Gafni | grad student | 2006 | University of Michigan | |
(The use of single-molecule detection in the resolution of complex enzyme kinetics.) | ||||
Duncan G. Steel | grad student | 2006 | University of Michigan (MichiganTree) | |
(The use of single-molecule detection in the resolution of complex enzyme kinetics.) | ||||
Yang Zhang | post-doc | University of Michigan | ||
Ayyalusamy Ramamoorthy | post-doc | 2006-2009 | NCI, NIH |
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Publications
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Kishimoto S, Devasahayam N, Chandramouli GVR, et al. (2023) Evaluation of a deuterated triarylmethyl spin probe for in vivo R ∗-based EPR oximetric imaging with enhanced dynamic range. Magnetic Resonance in Medicine |
Otowa Y, Kishimoto S, Saida Y, et al. (2023) Evofosfamide and Gemcitabine Act Synergistically in Pancreatic Cancer Xenografts by Dual Action on Tumor Vasculature and Inhibition of Homologous Recombination DNA Repair. Antioxidants & Redox Signaling |
Brender JR, Ramamoorthy A, Gursky O, et al. (2022) Intrinsic disorder and structural biology: Searching where the light isn't. Biophysical Chemistry. 292: 106912 |
AbuSalim JE, Yamamoto K, Miura N, et al. (2021) Simple Esterification of [1-C]-Alpha-Ketoglutarate Enhances Membrane Permeability and Allows for Noninvasive Tracing of Glutamate and Glutamine Production. Acs Chemical Biology |
Miura N, Mushti C, Sail D, et al. (2021) Synthesis of [1- C-5- C]-alpha-ketoglutarate enables noninvasive detection of 2-hydroxyglutarate. Nmr in Biomedicine. e4588 |
Yamamoto K, Opina A, Sail D, et al. (2021) Real-Time insight into in vivo redox status utilizing hyperpolarized [1-C] N-acetyl cysteine. Scientific Reports. 11: 12155 |
Saida Y, Brender JR, Yamamoto K, et al. (2021) Multimodal molecular imaging detects early responses to immune checkpoint blockade. Cancer Research |
Kishimoto S, Brender J, Chandramouli GVR, et al. (2020) Hypoxia activated prodrug evofosfamide treatment in pancreatic ductal adenocarcinoma xenografts alters the tumor redox status to potentiate radiotherapy. Antioxidants & Redox Signaling |
Ratha BN, Kar RK, Brender JR, et al. (2020) High Resolution Structure of A Partially Folded Insulin Aggregation Intermediate. Proteins |
Yamamoto K, Brender JR, Seki T, et al. (2020) Molecular Imaging of the Tumor Microenvironment reveals the Relationship between Tumor Oxygenation, Glucose Uptake and Glycolysis in Pancreatic Ductal Adenocarcinoma. Cancer Research |