James E. Rothman
Affiliations: | 1978-1988 | Biochemistry | Stanford University, Palo Alto, CA |
| 1988-1991 | Molecular Biology | Princeton University, Princeton, NJ | |
| 1991-2004 | Cellular Biochemistry and Biophysics | Memorial Sloan-Kettering Cancer Center, Rockville Centre, NY, United States | |
| 2004-2008 | Cellular Biophysics | Columbia University, New York, NY | |
| 2008- | Cell Biology | Yale University, New Haven, CT |
Area:
Secretion, membrane fusionWebsite:
https://www.nobelprize.org/nobel_prizes/medicine/laureates/2013/rothman-bio.htmlGoogle:
"James E. Rothman"Bio:
Discovered most of the eukaryotic SNARE-mediated membrane fusion machinery
The Nobel Prize in Physiology or Medicine 2013 was awarded jointly to James E. Rothman, Randy W. Schekman and Thomas C. Südhof "for their discoveries of machinery regulating vesicle traffic, a major transport system in our cells".
http://www.nasonline.org/member-directory/members/64187.html
https://medicine.yale.edu/cellbio/people/james_rothman.profile
https://chem.yale.edu/people/james-rothman
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Mean distance: 8.5 (cluster 21) | S | N | B | C | P |
Cross-listing: Cell Biology Tree
Parents
Sign in to add mentor| Marshall Fixman | research assistant | 1969-1970 | Yale | |
| Harold J. Morowitz | research assistant | 1970-1971 | Yale | |
| (Senior thesis) | ||||
| Eugene Patrick Kennedy | grad student | 1976 | Harvard Medical School | |
| (Transbilayer asymmetry and its maintenance in biological membranes) | ||||
| Harvey F. Lodish | post-doc | 1976-1978 | MIT | |
Children
Sign in to add trainee| Robert J Johnston | research assistant | (Neurotree) | |
| Con Beckers | grad student | (Cell Biology Tree) | |
| William G. Dunphy | grad student | Caltech | |
| Andreas M. Ernst | grad student | Yale School of Medicine (Cell Biology Tree) | |
| Sandra Schmid | grad student | Stanford (Cell Biology Tree) | |
| John L. R. Rubenstein | grad student | 1980-1982 | Stanford (Neurotree) |
| Benjamin Glick | grad student | 1983-1988 | Stanford (Cell Biology Tree) |
| Tobias M. Hohl | grad student | 1995-2000 | |
| Daniel T. Radoff | grad student | 2007-2011 | Columbia |
| Lena K Schroder | grad student | 2008-2014 | Yale (Cell Biology Tree) |
| Sarah M. Auclair | post-doc | Yale School of Medicine | |
| William E. Balch | post-doc | Stanford (Cell Biology Tree) | |
| Frantz Brückert | post-doc | ||
| Lara K. Mahal | post-doc | Sloan-Kettering | |
| Vivek Malhotra | post-doc | Stanford (Cell Biology Tree) | |
| Gero Miesenbock | post-doc | Memorial Sloan Kettering (Neurotree) | |
| Abdou Rachid Thiam | post-doc | (Cell Biology Tree) | |
| Peggy J. Weidman | post-doc | Princeton (Neurotree) | |
| Ai Yamamoto | post-doc | (Neurotree) | |
| Suzanne R. Pfeffer | post-doc | 1984-1985 | Stanford |
| Michael Brunner | post-doc | 1989-1991 | Heidelberg University (Cell Biology Tree) |
| Martin Gerard (Gerry) Waters | post-doc | 1990-1992 | Princeton (Cell Biology Tree) |
| Sidney W. Whiteheart | post-doc | 1994 | Memorial Sloan-Kettering Cancer Center |
| Giampietro Schiavo | post-doc | 1996 | Memorial Sloan-Kettering Cancer Center (Neurotree) |
| James A. McNew | post-doc | 1995-2000 | Memorial Sloan-Kettering Cancer Center |
| Greg Lavieu | post-doc | 2006-2015 | (Cell Biology Tree) |
| Sathish Ramakrishnan | post-doc | 2015-2019 | |
| Erdem Karatekin | research scientist | 2008-2011 | Yale |
BETA: Related publications
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Publications
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| Schueder F, Rivera-Molina F, Su M, et al. (2024) Unraveling cellular complexity with transient adapters in highly multiplexed super-resolution imaging. Cell. 187: 1769-1784.e18 |
| Brown C, Ghosh S, McAllister R, et al. (2024) A proteome-wide quantitative guide for nanoscale spatially resolved extraction of membrane proteins into native nanodiscs. Biorxiv : the Preprint Server For Biology |
| Bera M, Radhakrishnan A, Coleman J, et al. (2023) Synaptophysin chaperones the assembly of 12 SNAREpins under each ready-release vesicle. Proceedings of the National Academy of Sciences of the United States of America. 120: e2311484120 |
| Rothman JE, Grushin K, Bera M, et al. (2023) Turbocharging synaptic transmission. Febs Letters. 597: 2233-2249 |
| Kalyana Sundaram RV, Chatterjee A, Bera M, et al. (2023) Roles for diacylglycerol in synaptic vesicle priming and release revealed by complete reconstitution of core protein machinery. Proceedings of the National Academy of Sciences of the United States of America. 120: e2309516120 |
| Bera M, Grushin K, Sundaram RVK, et al. (2023) Two successive oligomeric Munc13 assemblies scaffold vesicle docking and SNARE assembly to support neurotransmitter release. Biorxiv : the Preprint Server For Biology |
| Bera M, Radhakrishnan A, Coleman J, et al. (2023) Synaptophysin Chaperones the Assembly of 12 SNAREpins under each Ready-Release Vesicle. Biorxiv : the Preprint Server For Biology |
| Sundaram RVK, Chatterjee A, Bera M, et al. (2023) Novel Roles for Diacylglycerol in Synaptic Vesicle Priming and Release Revealed by Complete Reconstitution of Core Protein Machinery. Biorxiv : the Preprint Server For Biology |
| Panda A, Giska F, Duncan AL, et al. (2023) Direct determination of oligomeric organization of integral membrane proteins and lipids from intact customizable bilayer. Nature Methods |
| Rothman JE. (2022) The gripping story of integrins. Cell |