Jennifer L. Leight, Ph.D.

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Tissue Microfabrication
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SNBCP

Parents

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Christopher S. Chen grad student 2011 Penn (BME Tree)
 (Regulation of TGF-B1-induced apoptosis and epithelial-mesenchymal transition by matrix rigidity.)

Children

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Joe Sharick post-doc 2019- Ohio State (BME Tree)
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Publications

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Dedhia PH, Sivakumar H, Rodriguez MA, et al. (2023) A 3D adrenocortical carcinoma tumor platform for preclinical modeling of drug response and matrix metalloproteinase activity. Scientific Reports. 13: 15508
Tahara S, de Faria FCC, Sarchet P, et al. (2023) Three dimensional models of dedifferentiated liposarcoma cell lines: scaffold-based and scaffold-free approaches. Human Cell
Dedhia PH, Sivakumar H, Rodriguez MA, et al. (2023) A 3D adrenocortical carcinoma tumor platform for preclinical modeling of drug response and matrix metalloproteinase activity. Biorxiv : the Preprint Server For Biology
Jones CE, Sharick JT, Sizemore ST, et al. (2022) A miniaturized screening platform to identify novel regulators of extracellular matrix alignment. Cancer Research Communications. 2: 1471-1486
Sharick JT, Atieh AJ, Gooch KJ, et al. (2022) Click chemistry functionalization of self-assembling peptide hydrogels. Journal of Biomedical Materials Research. Part A
Nairon KG, DePalma TJ, Zent JM, et al. (2022) Tumor cell-conditioned media drives collagen remodeling via fibroblast and pericyte activation in an premetastatic niche model. Iscience. 25: 104645
Jones CE, Sharick JT, Colbert SE, et al. (2021) Pten regulates collagen fibrillogenesis by fibroblasts through SPARC. Plos One. 16: e0245653
Wormsbaecher C, Hindman AR, Avendano A, et al. (2020) In utero estrogenic endocrine disruption alters the stroma to increase extracellular matrix density and mammary gland stiffness. Breast Cancer Research : Bcr. 22: 41
Casadei L, Calore F, Braggio DA, et al. (2019) MDM2 derived from dedifferentiated liposarcoma extracellular vesicles induces MMP2 production from preadipocytes. Cancer Research
Campbell WA, Deshmukh A, Blum S, et al. (2019) Matrix-metalloproteinase expression and gelatinase activity in the avian retina and their influence on Müller glia proliferation. Experimental Neurology. 112984
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