Rajarshi Guha, Ph.D.

Affiliations: 
Pennsylvania State University, State College, PA, United States 
Area:
Computational Chemistry
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"Rajarshi Guha"
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Peter C. Jurs grad student 2005 Penn State
 (Methods to improve the reliability, validity and interpretability of QSAR models.)
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Publications

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Harrington BS, Ozaki MK, Caminear MW, et al. (2020) Drugs Targeting Tumor-Initiating Cells Prolong Survival in a Post-Surgery, Post-Chemotherapy Ovarian Cancer Relapse Model. Cancers. 12
Wei D, Yang Y, Ricketts CJ, et al. (2020) Novel renal medullary carcinoma cell lines, UOK353 and UOK360, provide preclinical tools to identify new therapeutic treatments. Genes, Chromosomes & Cancer
Lin GL, Wilson KM, Ceribelli M, et al. (2019) Therapeutic strategies for diffuse midline glioma from high-throughput combination drug screening. Science Translational Medicine. 11
Bandyopadhyay D, Kreatsoulas C, Brady PG, et al. (2019) Scaffold-Based Analytics: Enabling Hit-to-Lead Decisions by Visualizing Chemical Series Linked Across Large Datasets. Journal of Chemical Information and Modeling
Lee TD, Lee OW, Brimacombe KR, et al. (2019) A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular Pharmacology
Alkhilaiwi F, Paul S, Zhou D, et al. (2019) High-throughput screening identifies candidate drugs for the treatment of recurrent respiratory papillomatosis. Papillomavirus Research (Amsterdam, Netherlands). 100181
Bian Y, Teper Y, Mathews Greiner LA, et al. (2019) Target deconvolution of a multikinase inhibitor with anti-metastatic properties identifies TAOK3 as a key contributor to a cancer stem cell-like phenotype. Molecular Cancer Therapeutics
Huang R, Grishagin I, Wang Y, et al. (2019) The NCATS BioPlanet - An Integrated Platform for Exploring the Universe of Cellular Signaling Pathways for Toxicology, Systems Biology, and Chemical Genomics. Frontiers in Pharmacology. 10: 445
Kearney SE, Zahoránszky-Kőhalmi G, Brimacombe KR, et al. (2018) Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space. Acs Central Science. 4: 1727-1741
Iniguez AB, Alexe G, Wang EJ, et al. (2018) Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling. Cancer Cell. 34: 922-938.e7
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