Alana G. Lerner, Ph.D.

Affiliations: 
Biomedical Sciences University of California, San Francisco, San Francisco, CA 
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Feroz Papa grad student 2011 UCSF
 (Investigation of apoptosis under endoplasmic reticulum stress during diabetes pathogenesis.)
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Publications

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Acosta-Alvear D, Cho MY, Wild T, et al. (2015) Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits. Elife. 4
Acosta-Alvear D, Cho MY, Wild T, et al. (2015) Author response: Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits Elife
Masto VB, Lerner AG, Arastu-Kapur S. (2015) Abstract 1735: Identification of novel synthetic lethal interactions in small cell lung cancer with the proteasome inhibitor carfilzomib Cancer Research. 75: 1735-1735
Lin T, Lerner A, Kirk CJ, et al. (2013) Survival Pathways Stabilized By Proteasome Inhibition Reveal PIM2 As a Novel Target For Potentiating The Anti-Myeloma Activity Of Carfilzomib Blood. 122: 4440-4440
Lowe E, Maglathlin R, Lerner A, et al. (2013) Blocking Protein Secretion and Degradation Is a Novel Treatment Strategy For Malignant Cells With High Protein Load Blood. 122: 4439-4439
Lerner AG, Upton JP, Praveen PV, et al. (2012) IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. Cell Metabolism. 16: 250-64
Han D, Lerner AG, Vande Walle L, et al. (2009) IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. Cell. 138: 562-75
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