Brian M. Cochran, Ph.D.

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
Organic and Organometallic Chemistry
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"Brian Cochran"
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Forrest E. Michael grad student 2009 University of Washington
 (The development and mechanistic studies of palladium catalyzed hydroamination and metal-free oxidative amination reactions.)
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Publications

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Cochran BM, Corbett MT, Correll TL, et al. (2018) Development of a Commercial Process to Prepare AMG 232 Using A Green Ozonolysis-Pinnick Tandem Transformation. The Journal of Organic Chemistry
Rovis T, Oberg K, Cochran B, et al. (2018) The Catalytic Alkylative Desymmetrization of Anhydrides in a Formal Synthesis of Ionomycin Synthesis. 50: 4343-4350
Rovis T, Cochran B, Henderson D, et al. (2017) Rhodium-Catalyzed Desymmetrization of meso-Glutaric Anhydrides to Access Enantioenriched anti,anti-Polypropionates Synlett. 29: 306-309
Cochran BM. (2016) One-pot oxidative cleavage of olefins to synthesize carboxylic acids by a telescoped ozonolysis-oxidation process Synlett. 27: 245-248
McGhee A, Cochran BM, Stenmark TA, et al. (2013) Stereoselective synthesis of 2,5-disubstituted morpholines using a palladium-catalyzed hydroamination reaction. Chemical Communications (Cambridge, England). 49: 6800-2
Cochran BM, Michael FE. (2008) Metal-free oxidative cyclization of urea-tethered alkenes with hypervalent iodine. Organic Letters. 10: 5039-42
Cochran BM, Michael FE. (2008) Mechanistic studies of a palladium-catalyzed intramolecular hydroamination of unactivated alkenes: protonolysis of a stable palladium alkyl complex is the turnover-limiting step. Journal of the American Chemical Society. 130: 2786-92
Michael FE, Sibbald PA, Cochran BM. (2008) Palladium-catalyzed intramolecular chloroamination of alkenes. Organic Letters. 10: 793-6
Cochran BM, Michael FE. (2008) Synthesis of 2,6-disubstituted piperazines by a diastereoselective palladium-catalyzed hydroamination reaction. Organic Letters. 10: 329-32
Michael FE, Cochran BM. (2006) Room temperature palladium-catalyzed intramolecular hydroamination of unactivated alkenes. Journal of the American Chemical Society. 128: 4246-7
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