Atul Jain, Ph.D.

Affiliations: 
Pharmaceutical Sciences Virginia Commonwealth University, Richmond, VA, United States 
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Richard A. Glennon grad student 2013 VCU
 (Positive allosteric modulators of alpha4beta2 neuronal nicotinic acetylcholine receptors: Synthesis and in vitro studies.)
Terry Moore post-doc 2013-2016 University of Illinois, Chicago
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Publications

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Lazzara PR, Jain AD, Maldonado AC, et al. (2020) Synthesis and Evaluation of Noncovalent Naphthalene-Based KEAP1-NRF2 Inhibitors. Acs Medicinal Chemistry Letters. 11: 521-527
Richardson B, Jain AD, Potteti H, et al. (2018) Replacement of a Naphthalene Scaffold in Kelch-like ECH-Associated Protein 1 (KEAP1)/Nuclear factor (erythroid-derived 2)-like 2 (NRF2)Inhibitors. Journal of Medicinal Chemistry
Dukat M, Jain AD, German N, et al. (2018) des-Formylflustrabromine (dFBr): A Structure-Activity Study on its Ability to Potentiate the Action of Acetylcholine at α4β2 Nicotinic Acetylcholine Receptors. Acs Chemical Neuroscience
Yao Y, Kong C, Yin L, et al. (2016) Time-gated detection of cystathionine γ-lyase activity and inhibition with a selective, luminogenic hydrogen sulfide sensor. Chemistry (Weinheim An Der Bergstrasse, Germany)
Jain AD, Potteti H, Richardson BG, et al. (2015) Probing the structural requirements of non-electrophilic naphthalene-based Nrf2 activators. European Journal of Medicinal Chemistry. 103: 252-268
Kolanos R, Sakloth F, Jain AD, et al. (2015) Structural Modification of the Designer Stimulant α-Pyrrolidinovalerophenone (α-PVP) Influences Potency at Dopamine Transporters. Acs Chemical Neuroscience
Richardson BG, Jain AD, Speltz TE, et al. (2015) Non-electrophilic modulators of the canonical Keap1/Nrf2 pathway. Bioorganic & Medicinal Chemistry Letters. 25: 2261-8
Hamouda AK, Wang ZJ, Stewart DS, et al. (2015) Desformylflustrabromine (dFBr) and [3H]dFBr-Labeled Binding Sites in a Nicotinic Acetylcholine Receptor. Molecular Pharmacology. 88: 1-11
German N, Kim JS, Jain A, et al. (2011) Deconstruction of the α4β2 nicotinic acetylcholine receptor positive allosteric modulator desformylflustrabromine Journal of Medicinal Chemistry. 54: 7259-7267
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