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John R. Murphy, PhD

Affiliations:	1984	Microbiology and Molecular Genetics	Harvard Medical School, Boston, MA, United States
	1984-	Microbiology	Boston University School of Medicine, Boston, MA

Area:

molecular biology and molecular genetics of bacterial protein toxins

Website:

http://www.bu.edu/neidl/research/researchers/john-r-murphy-ph-d/

Google:

"John Richard Murphy"

Bio:

http://aem.asm.org/content/24/2/283.short
DOI: 10.1099/00221287-73-2-339
http://www.pnas.org/content/71/1/11.short

Mean distance: 8.65

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Parents

Richard C. Tilton	grad student	1972	University of Connecticut Health Center
(Purification and characterization of thiosulfate : cyanide sulfur transferase from Thiobacillus sp. strain IV-85)
Alwin M. Pappenheimer, Jr	post-doc	1972-1974	Harvard

Children

James Laurence Michel	grad student	1982	Harvard Medical School
William R. Bishai	grad student	1989	Harvard Medical School
Pankaj Kumar	post-doc	2017-	Johns Hopkins University School of Medicine; NYU Langone Medical center

Collaborators

BETA: Related publications

Publications

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Parveen S, Shen J, Lun S, et al. (2023) Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis. Nature Communications. 14: 7427
Parveen S, Shen J, Lun S, et al. (2023) Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against . Biorxiv : the Preprint Server For Biology
Parveen S, Lun S, Urbanowski ME, et al. (2021) Effective host-directed therapy for tuberculosis by targeted depletion of myeloid-derived suppressor cells and related cells using a diphtheria toxin-based fusion protein. The Journal of Infectious Diseases
Parveen S, Siddharth S, Cheung LS, et al. (2021) Therapeutic targeting with DABIL-4 depletes myeloid suppressor cells in 4T1 triple-negative breast cancer model. Molecular Oncology
Kumar P, Kumar A, Parveen S, et al. (2019) Recent advances with Treg depleting fusion protein toxins for cancer immunotherapy. Immunotherapy
Parveen S, Bishai WR, Murphy JR. (2019) : Diphtheria Toxin, the Operon, and Its Regulation by Fe2 Activation of apo-DtxR. Microbiology Spectrum. 7
Cheung LS, Fu J, Kumar P, et al. (2019) Second-generation IL-2 receptor-targeted diphtheria fusion toxin exhibits antitumor activity and synergy with anti-PD-1 in melanoma. Proceedings of the National Academy of Sciences of the United States of America
Gupta S, Cheung L, Pokkali S, et al. (2017) Suppressor Cell-Depleting Immunotherapy With Denileukin Diftitox is an Effective Host-Directed Therapy for Tuberculosis. The Journal of Infectious Diseases. 215: 1883-1887
Ando M, Manabe YC, Converse PJ, et al. (2003) Characterization of the role of the divalent metal ion-dependent transcriptional repressor MntR in the virulence of Staphylococcus aureus. Infection and Immunity. 71: 2584-90
Brennan PJ, Terwilliger T, Barry CE, et al. (2002) The US-Japan Cooperative Medical Science Program Tuberculosis and Leprosy Panel's 36th annual research conference, New Orleans, Louisiana, USA, 15-17 July 2001 Tuberculosis. 82: 113-135

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