Luke W. Arbogast, Ph.D.

Affiliations: 
Chemistry Johns Hopkins University, Baltimore, MD 
Area:
macromolecular structure and dynamics in solution
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"Luke Arbogast"
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Parents

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Joel R. Tolman grad student 2013 Johns Hopkins
 (Methodological advancements for the measurement of residual anisotropic spin interactions in proteins by NMR spectroscopy.)
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Publications

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Perodeau J, Arbogast LW, Nieuwkoop AJ. (2023) Solid-State NMR Characterization of Lyophilized Formulations of Monoclonal Antibody Therapeutics. Molecular Pharmaceutics
Elliott KW, Delaglio F, Wikström M, et al. (2021) Principal Component Analysis of 1D ¹H Diffusion Edited NMR Spectra of Protein Therapeutics. Journal of Pharmaceutical Sciences
Sheen DA, Shen VK, Brinson RG, et al. (2020) Chemometric Outlier Classification of 2D-NMR Spectra to Enable Higher Order Structure Characterization of Protein Therapeutics. Chemometrics and Intelligent Laboratory Systems : An International Journal Sponsored by the Chemometrics Society. 199
Brinson RG, Elliott KW, Arbogast LW, et al. (2020) Principal component analysis for automated classification of 2D spectra and interferograms of protein therapeutics: influence of noise, reconstruction details, and data preparation. Journal of Biomolecular Nmr
Arbogast LW, Delaglio F, Brinson RG, et al. (2020) Assessment of the Higher-Order Structure of Formulated Monoclonal Antibody Therapeutics by 2D Methyl Correlated NMR and Principal Component Analysis. Current Protocols in Protein Science. 100: e105
Elliott KW, Ghasriani H, Wikström M, et al. (2020) Comparative Analysis of One-Dimensional Protein Fingerprint by Line Shape Enhancement and Two-Dimensional H,C Methyl NMR Methods for Characterization of the Higher Order Structure of IgG1 Monoclonal Antibodies. Analytical Chemistry
Brinson RG, Arbogast LW, Marino JP, et al. (2020) Best Practices in Utilization of 2D-NMR Spectral Data as the Input for Chemometric Analysis in Biopharmaceutical Applications. Journal of Chemical Information and Modeling
Sheen DA, Shen VK, Brinson RG, et al. (2020) Chemometric outlier classification of 2D-NMR spectra to enable higher order structure characterization of protein therapeutics Chemometrics and Intelligent Laboratory Systems. 199: 103973
Tolman JR, Arbogast LW. (2019) Selective spin inversion in solution by magic field cross polarization. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 308: 106588
Brinson RG, Marino JP, Delaglio F, et al. (2018) Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics. Mabs
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