Christopher J. Creighton, Ph.D.

peptides

Murray Goodman	grad student	2000	UCSD
(Reagents and reactions for peptidomimetic drug design.)

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Romoff TT, Ignacio BG, Mansour N, et al. (2020) Large-Scale Synthesis of the Glycine Schiff Base Ni(II) Complex Derived from (S)- and (R)-N-(2-Benzoyl-4-chlorophenyl)-1-[(3,4-dichlorophenyl)methyl]-2-pyrrolidinecarboxamide Organic Process Research & Development. 24: 294-300
Romoff TT, Palmer AB, Mansour N, et al. (2017) Scale-up Synthesis of (R)- and (S)-N-(2-Benzoyl-4-chlorophenyl)-1-(3,4-dichlorobenzyl)pyrrolidine-2-carboxamide Hydrochloride, A Versatile Reagent for the Preparation of Tailor-Made α- and β-Amino Acids in an Enantiomerically Pure Form Organic Process Research & Development. 21: 732-739
Zapf CW, Creighton CJ, Tomioka M, et al. (2001) A novel traceless resin-bound guanidinylating reagent for secondary amines to prepare N,N-disubstituted guanidines. Organic Letters. 3: 1133-6
Creighton CJ, Zapf CW, Bu JH, et al. (1999) Solid-phase synthesis of pyridones and pyridopyrazines as peptidomimetic scaffolds. Organic Letters. 1: 1407-9
Creighton CJ, Romoff TT, Bu JH, et al. (1999) Mechanistic studies of an unusual amide bond scission Journal of the American Chemical Society. 121: 6786-6791