Kyle R. Spinler, Ph.D.
Affiliations: | Chemical and Biomolecular Engineering | University of Pennsylvania, Philadelphia, PA, United States |
Area:
cell biophysics and polymer engineeringGoogle:
"Kyle Spinler"Mean distance: 11.23 | S | N | B | C | P |
Parents
Sign in to add mentor| Dennis E. Discher | grad student | 2014 | Penn | |
| (Membrane forces and key protein determinants of hematopoietic cell function: Lamins and myosin-II in hematopoiesis and CD47 in immunotherapy of cancer.) | ||||
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Publications
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| Alvey CM, Spinler KR, Irianto J, et al. (2017) SIRPA-Inhibited, Marrow-Derived Macrophages Engorge, Accumulate, and Differentiate in Antibody-Targeted Regression of Solid Tumors. Current Biology : Cb |
| Ivanovska IL, Swift J, Spinler K, et al. (2017) Cross-linked matrix rigidity and soluble retinoids synergize in nuclear lamina regulation of stem cell differentiation. Molecular Biology of the Cell |
| Nair PR, Karthick SA, Spinler KR, et al. (2016) Filomicelles from aromatic diblock copolymers increase paclitaxel-induced tumor cell death and aneuploidy compared with aliphatic copolymers. Nanomedicine (London, England) |
| Alvey C, Spinler K, Tewari M, et al. (2016) 511. Engineered Donor Marrow Macrophages Phagocytose Cancer Cells and Aggressively Shrink Solid Tumor Xenografts Compared to Tumor Associated Macrophages Molecular Therapy. 24: S204 |
| Ivanovska IL, Swift J, Spinler K, et al. (2016) Matrix and Soluble Factor Pathways to Lineage Specification Biophysical Journal. 110: 95a |
| Nair PR, Spinler KR, Vakili MR, et al. (2016) Filovirus Mimics Deliver Effectively Biophysical Journal. 110: 504a |
| Sosale NG, Spinler KR, Alvey C, et al. (2015) Macrophage engulfment of a cell or nanoparticle is regulated by unavoidable opsonization, a species-specific 'Marker of Self' CD47, and target physical properties. Current Opinion in Immunology. 35: 107-112 |
| Spinler KR, Shin JW, Lambert MP, et al. (2015) Myosin-II repression favors pre/proplatelets but shear activation generates platelets and fails in macrothrombocytopenia. Blood. 125: 525-33 |
| Alvey CM, Spinler K, Tewari M, et al. (2015) Engineered Donor Marrow Macrophages Phagocytose Cancer Cells and Aggressively Shrink Solid Tumor Xenografts Compared to Tumor Associated Macrophages Blood. 126: 2214-2214 |
| Ivanovska IL, Swift J, Spinler K, et al. (2015) Cross-Linked Matrix Rigidity and Soluble Factors Induce Differentiation via Distinct but Overlapping Pathways Biophysical Journal. 108: 560a-561a |