Michaeleen C. Doucleff, Ph.D.

Affiliations: 
2007 University of California, Berkeley, Berkeley, CA, United States 
Area:
Biophysical Chemistry: Proteins, Nucleic Acids, NMR Spectroscopy
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"Michaeleen Doucleff"
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David E. Wemmer grad student 2007 UC Berkeley
 (Structures and mechanisms of bacterial sigma54 -dependent transcription initiation.)
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Publications

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Batchelor JD, Lee PS, Wang AC, et al. (2013) Structural mechanism of GAF-regulated σ(54) activators from Aquifex aeolicus. Journal of Molecular Biology. 425: 156-70
Anthis NJ, Doucleff M, Clore GM. (2011) Transient, sparsely populated compact states of apo and calcium-loaded calmodulin probed by paramagnetic relaxation enhancement: interplay of conformational selection and induced fit. Journal of the American Chemical Society. 133: 18966-74
Fawzi NL, Phillips AH, Ruscio JZ, et al. (2011) Structure and dynamics of the Aβ 21-30 peptide from the interplay of NMR experiments and molecular simulations (Journal of the American Chemical Society (2008) 130 (6145-6158) DOI: 10.1021/ja710366c) Journal of the American Chemical Society. 133: 11816
Fawzi NL, Doucleff M, Suh JY, et al. (2010) Mechanistic details of a protein-protein association pathway revealed by paramagnetic relaxation enhancement titration measurements. Proceedings of the National Academy of Sciences of the United States of America. 107: 1379-84
Hong E, Doucleff M, Wemmer DE. (2009) Structure of the RNA polymerase core-binding domain of sigma(54) reveals a likely conformational fracture point. Journal of Molecular Biology. 390: 70-82
Batchelor JD, Doucleff M, Lee CJ, et al. (2008) Structure and regulatory mechanism of Aquifex aeolicus NtrC4: variability and evolution in bacterial transcriptional regulation. Journal of Molecular Biology. 384: 1058-75
Doucleff M, Clore GM. (2008) Global jumping and domain-specific intersegment transfer between DNA cognate sites of the multidomain transcription factor Oct-1. Proceedings of the National Academy of Sciences of the United States of America. 105: 13871-6
Fawzi NL, Phillips AH, Ruscio JZ, et al. (2008) Structure and dynamics of the Abeta(21-30) peptide from the interplay of NMR experiments and molecular simulations. Journal of the American Chemical Society. 130: 6145-58
Doucleff M, Pelton JG, Lee PS, et al. (2007) Structural basis of DNA recognition by the alternative sigma-factor, sigma54. Journal of Molecular Biology. 369: 1070-8
Chen B, Doucleff M, Wemmer DE, et al. (2007) ATP ground- and transition states of bacterial enhancer binding AAA+ ATPases support complex formation with their target protein, sigma54. Structure (London, England : 1993). 15: 429-40
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