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Fu-Yang Lin, Ph.D.

Affiliations: 
2011 School of Molecular & Cell Bio University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
biomolecular NMR
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"Fu-Yang Lin"
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Eric Oldfield grad student 2011 UIUC
 (Head-to-head terpene synthases: Mechanism of action and inhibition.)

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Publications

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Lin FY, Liu YL, Li K, et al. (2012) Head-to-head prenyl tranferases: anti-infective drug targets. Journal of Medicinal Chemistry. 55: 4367-72
Lin FY, Zhang Y, Hensler M, et al. (2012) Dual dehydrosqualene/squalene synthase inhibitors: leads for innate immune system-based therapeutics. Chemmedchem. 7: 561-4
Oldfield E, Lin FY. (2012) Terpene biosynthesis: modularity rules. Angewandte Chemie (International Ed. in English). 51: 1124-37
Oldfield E, Lin F. (2012) Terpen-Biosynthese: Modularitätsregeln Angewandte Chemie. 124: 1150-1163
Lin FY, Liu CI, Liu YL, et al. (2010) Mechanism of action and inhibition of dehydrosqualene synthase. Proceedings of the National Academy of Sciences of the United States of America. 107: 21337-42
Cao R, Zhang Y, Mann FM, et al. (2010) Diterpene cyclases and the nature of the isoprene fold. Proteins. 78: 2417-32
Ramos IB, Miranda K, Pace DA, et al. (2010) Calcium- and polyphosphate-containing acidic granules of sea urchin eggs are similar to acidocalcisomes, but are not the targets for NAADP. The Biochemical Journal. 429: 485-95
Zhang Y, Cao R, Yin F, et al. (2010) Lipophilic pyridinium bisphosphonates: potent gammadelta T cell stimulators. Angewandte Chemie (International Ed. in English). 49: 1136-8
Song Y, Liu CI, Lin FY, et al. (2009) Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results. Journal of Medicinal Chemistry. 52: 3869-80
Zhang Y, Cao R, Yin F, et al. (2009) Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation. Journal of the American Chemical Society. 131: 5153-62
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