Nicholas R. Wurtz, Ph.D.
Affiliations: | 2002 | California Institute of Technology, Pasadena, CA |
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"Nicholas Wurtz"Mean distance: 7.52 | S | N | B | C | P |
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Sign in to add mentor| Peter B. Dervan | grad student | 2002 | Caltech | |
| (Sequence-specific alkylation of DNA by polyamide -chlorambucil conjugates.) | ||||
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| Szpilman AM, Cereghetti DM, Manthorpe JM, et al. (2009) Synthesis and biophysical studies on 35-deoxy amphotericin B methyl ester. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 7117-28 |
| Szpilman AM, Cereghetti DM, Wurtz NR, et al. (2008) Synthesis of 35-deoxy amphotericin B methyl ester: a strategy for molecular editing. Angewandte Chemie (International Ed. in English). 47: 4335-8 |
| Dudouet B, Burnett R, Dickinson LA, et al. (2003) Accessibility of nuclear chromatin by DNA binding polyamides. Chemistry & Biology. 10: 859-67 |
| Wang YD, Dziegielewski J, Wurtz NR, et al. (2003) DNA crosslinking and biological activity of a hairpin polyamide-chlorambucil conjugate. Nucleic Acids Research. 31: 1208-15 |
| Belitsky JM, Nguyen DH, Wurtz NR, et al. (2002) Solid-phase synthesis of DNA binding polyamides on oxime resin. Bioorganic & Medicinal Chemistry. 10: 2767-74 |
| Wurtz NR, Pomerantz JL, Baltimore D, et al. (2002) Inhibition of DNA binding by NF-kappa B with pyrrole-imidazole polyamides. Biochemistry. 41: 7604-9 |
| Bremer RE, Wurtz NR, Szewczyk JW, et al. (2001) Inhibition of major groove DNA binding bZIP proteins by positive patch polyamides. Bioorganic & Medicinal Chemistry. 9: 2093-103 |
| Wurtz NR, Turner JM, Baird EE, et al. (2001) Fmoc solid phase synthesis of polyamides containing pyrrole and imidazole amino acids. Organic Letters. 3: 1201-3 |
| Wurtz NR, Dervan PB. (2000) Sequence specific alkylation of DNA by hairpin pyrrole-imidazole polyamide conjugates. Chemistry & Biology. 7: 153-61 |