Rong Gao, Ph.D.
Affiliations: | 2005 | University of Virginia, Charlottesville, VA |
Area:
Natural products, BleomycinGoogle:
"Rong Gao"Mean distance: 9.38 | S | N | B | C | P |
Parents
Sign in to add mentor| Sidney M. Hecht | grad student | 2005 | UVA | |
| (Analysis of the mechanism of type IB topoisomerases.) | ||||
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Publications
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| Elban MA, Sun W, Eisenhauer BM, et al. (2006) Synthesis and biological evaluation of 10,11-methylenedioxy-14-azacamptothecin. Organic Letters. 8: 3513-6 |
| Gao R, Zhang Y, Dedkova L, et al. (2006) Effects of modification of the active site tyrosine of human DNA topoisomerase I. Biochemistry. 45: 8402-10 |
| Gao R, Zhang Y, Choudhury AK, et al. (2005) Analogues of vaccinia virus DNA topoisomerase I modified at the active site tyrosine. Journal of the American Chemical Society. 127: 3321-31 |
| Rahier NJ, Cheng K, Gao R, et al. (2005) Synthesis of 14-azacamptothecin, a water-soluble topoisomerase I poison. Organic Letters. 7: 835-7 |
| Rahier NJ, Eisenhauer BM, Gao R, et al. (2005) On the role of E-ring oxygen atoms in the binding of camptothecin to the topoisomerase I-DNA covalent binary complex. Bioorganic & Medicinal Chemistry. 13: 1381-6 |
| Cheng K, Rahier NJ, Eisenhauer BM, et al. (2005) 14-azacamptothecin: a potent water-soluble topoisomerase I poison. Journal of the American Chemical Society. 127: 838-9 |
| Cagir A, Eisenhauer BM, Gao R, et al. (2004) Synthesis and topoisomerase I inhibitory properties of luotonin A analogues. Bioorganic & Medicinal Chemistry. 12: 6287-99 |
| Gao R, Claeboe CD, Eisenhauer BM, et al. (2004) Identification of specific nonbridging phosphate oxygens important for DNA cleavage by human topoisomerase I. Biochemistry. 43: 6167-81 |
| Cagir A, Jones SH, Eisenhauer BM, et al. (2004) Synthesis and biochemical properties of E-ring modified luotonin A derivatives. Bioorganic & Medicinal Chemistry Letters. 14: 2051-4 |
| Rahier NJ, Eisenhauer BM, Gao R, et al. (2004) Water-soluble camptothecin derivatives that are intrinsic topoisomerase I poisons. Organic Letters. 6: 321-4 |