Chris Sfouggatakis, Ph.D.

Affiliations: 
2004 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Natural product synthesis
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"Chris Sfouggatakis"
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Amos B. Smith, III grad student 2004 Penn
 (Toward the gram -scale total synthesis of (+)-spongistatin 1.)
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La Cruz TE, González-Bobes F, Eastgate MD, et al. (2021) Scalable Asymmetric Synthesis of the All Triamino Cyclohexane Core of BMS-813160. The Journal of Organic Chemistry
Maity P, Reddy VVR, Mohan J, et al. (2018) Development of a Scalable Synthesis of BMS-978587 Featuring a Stereospecific Suzuki Coupling of a Cyclopropane Carboxylic Acid Organic Process Research & Development. 22: 888-897
Smith MJ, Lawler MJ, Kopp N, et al. (2017) Development of a Concise Multikilogram Synthesis of LPA-1 Antagonist BMS-986020 via a Tandem Borylation–Suzuki Procedure Organic Process Research & Development. 21: 1859-1863
Ortiz A, Benkovics T, Beutner GL, et al. (2015) Scalable Synthesis of the Potent HIV Inhibitor BMS-986001 by Non-Enzymatic Dynamic Kinetic Asymmetric Transformation (DYKAT). Angewandte Chemie (International Ed. in English). 54: 7185-8
Smith AB, Sfouggatakis C, Risatti CA, et al. (2009) Spongipyran Synthetic Studies. Evolution of a Scalable Total Synthesis of (+)-Spongistatin 1. Tetrahedron. 65: 6489-6509
Smith AB, Doughty VA, Sfouggatakis C, et al. (2009) Spongistatin synthetic studies. An efficient, second-generation construction of an advanced ABCD intermediate (Organic Letters (2002) 4) Organic Letters. 11: 785
Smith AB, Tomioka T, Risatti CA, et al. (2008) Gram-scale synthesis of (+)-spongistatin 1: development of an improved, scalable synthesis of the F-ring subunit, fragment union, and final elaboration. Organic Letters. 10: 4359-62
Smith AB, Sfouggatakis C, Gotchev DB, et al. (2004) Spongistatin synthetic studies. evolution of a scalable synthesis for the EF fragment of (+)-Spongistatin 1 exploiting a Petasis-Ferrier union/rearrangement tactic. Organic Letters. 6: 3637-40
Smith AB, Pitram SM, Boldi AM, et al. (2003) Multicomponent linchpin couplings. Reaction of dithiane anions with terminal epoxides, epichlorohydrin, and vinyl epoxides: efficient, rapid, and stereocontrolled assembly of advanced fragments for complex molecule synthesis. Journal of the American Chemical Society. 125: 14435-45
Smith AB, Zhu W, Shirakami S, et al. (2003) Total synthesis of (+)-spongistatin 1. An effective second-generation construction of an advanced EF Wittig salt, fragment union, and final elaboration. Organic Letters. 5: 761-4
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