Inchan Kwon, Ph.D.

Affiliations: 
2007 Chemical Engineering California Institute of Technology, Pasadena, CA 
Area:
artificial proteins
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"Inchan Kwon"
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Parents

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David A. Tirrell grad student 2007 Caltech
 (Protein engineering via site-specific incorporation of nonnatural amino acids.)

Children

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Sung In Lim grad student 2011-2015 UVA (Computational Biology Tree)
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Publications

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Park MY, Kim S, Kwon NH, et al. (2023) Enhanced anti-tumor activity of arginine decarboxylase through the incorporation of aromatic amino acids at the multimer forming interface. Biotechnology Journal. e2300453
Yang B, Kwon I. (2021) Chemical Modification of Cysteine with 3-Arylpropriolonitrile Improves the In Vivo Stability of Albumin-Conjugated Urate Oxidase Therapeutic Protein. Biomedicines. 9
Yang B, Kwon I. (2021) Thermostable and Long-Circulating Albumin-Conjugated Urate Oxidase. Pharmaceutics. 13
Yang B, Kwon I. (2021) Multivalent Albumin-Neonatal Fc Receptor Interactions Mediate a Prominent Extension of the Serum Half-Life of a Therapeutic Protein. Molecular Pharmaceutics
Cho J, Park J, Tae G, et al. (2020) The Minimal Effect of Linker Length for Fatty Acid Conjugation to a Small Protein on the Serum Half-Life Extension. Biomedicines. 8
Cho J, Park J, Kim S, et al. (2020) Intramolecular distance in the conjugate of urate oxidase and fatty acid governs FcRn binding and serum half-life in vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society
Cha J, Kwon I. (2018) Purification-Free, Target-Selective Immobilization of a Protein from Cell Lysates. Biotechnology Journal
Cho J, Lim SI, Yang BS, et al. (2017) Generation of therapeutic protein variants with the human serum albumin binding capacity via site-specific fatty acid conjugation. Scientific Reports. 7: 18041
Jung S, Kwon I. (2017) Synergistic Degradation of a Hyperuricemia-Causing Metabolite Using One-Pot Enzyme-Nanozyme Cascade Reactions. Scientific Reports. 7: 44330
Kwon I, Yang B. (2017) Bioconjugation and Active Site Design of Enzymes Using Non-natural Amino Acids Industrial & Engineering Chemistry Research. 56: 6535-6547
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