Ranepuradewage E. Chandrasena, Ph.D.
Affiliations: | 2006 | University of Illinois at Chicago, Chicago, IL, United States |
Area:
radical chemistryGoogle:
"Ranepuradewage Chandrasena"Mean distance: 8.63 | S | N | B | C | P |
Parents
Sign in to add mentor| Martin E. Newcomb | grad student | 2006 | University of Illinois, Chicago | |
| (Multiple electrophilic oxidants in cytochrome P450 and photochemical generation of compound I.) | ||||
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Publications
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| Michalsen BT, Gherezghiher TB, Choi J, et al. (2012) Selective estrogen receptor modulator (SERM) lasofoxifene forms reactive quinones similar to estradiol. Chemical Research in Toxicology. 25: 1472-83 |
| Chandrasena RE, Edirisinghe PD, Bolton JL, et al. (2008) Problematic detoxification of estrogen quinones by NAD(P)H-dependent quinone oxidoreductase and glutathione-S-transferase. Chemical Research in Toxicology. 21: 1324-9 |
| Newcomb M, Lansakara-P DS, Kim HY, et al. (2007) Products from enzyme-catalyzed oxidations of norcarenes. The Journal of Organic Chemistry. 72: 1128-33 |
| Newcomb M, Chandrasena RE, Lansakara-P DS, et al. (2007) Desaturase reactions complicate the use of norcarane as a mechanistic probe. Unraveling the mixture of twenty-plus products formed in enzyme-catalyzed oxidations of norcarane. The Journal of Organic Chemistry. 72: 1121-7 |
| Newcomb M, Zhang R, Chandrasena RE, et al. (2006) Cytochrome p450 compound I. Journal of the American Chemical Society. 128: 4580-1 |
| Newcomb M, Chandrasena RE. (2005) Highly reactive electrophilic oxidants in cytochrome P450 catalysis. Biochemical and Biophysical Research Communications. 338: 394-403 |
| Zhang R, Chandrasena RE, Martinez E, et al. (2005) Formation of compound I by photo-oxidation of compound II. Organic Letters. 7: 1193-5 |
| Chandrasena RE, Vatsis KP, Coon MJ, et al. (2004) Hydroxylation by the hydroperoxy-iron species in cytochrome P450 enzymes. Journal of the American Chemical Society. 126: 115-26 |
| Newcomb M, Aebisher D, Shen R, et al. (2003) Kinetic isotope effects implicate two electrophilic oxidants in cytochrome p450-catalyzed hydroxylations. Journal of the American Chemical Society. 125: 6064-5 |