Gary Frey, Ph.D.

Affiliations: 
2000 Brandeis University, Waltham, MA, United States 
Area:
mechanistic enzymology
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"Gary Frey"
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Robert Heinz Abeles grad student 2000 Brandeis
 (Part I. Chemical mechanism and inhibition of myristoyl CoA:protein N-myristoyl transferase. Part II. Inhibition of prostate-specific antigen.)
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Publications

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Xiao T, Frey G, Fu Q, et al. (2020) HIV-1 fusion inhibitors targeting the membrane-proximal external region of Env spikes. Nature Chemical Biology
Dev J, Park D, Fu Q, et al. (2016) Structural basis for membrane anchoring of HIV-1 envelope spike. Science (New York, N.Y.)
Chen J, Frey G, Peng H, et al. (2014) Mechanism of HIV-1 neutralization by antibodies targeting a membrane-proximal region of gp41. Journal of Virology. 88: 1249-58
Frey G, Chen J, Rits-Volloch S, et al. (2010) Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies. Nature Structural & Molecular Biology. 17: 1486-91
Frey G, Rits-Volloch S, Zhang XQ, et al. (2006) Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion. Proceedings of the National Academy of Sciences of the United States of America. 103: 13938-43
Huang X, Knoell CT, Frey G, et al. (2001) Modulation of recombinant human prostate-specific antigen: activation by Hofmeister salts and inhibition by azapeptides. Appendix: thermodynamic interpretation of the activation by concentrated salts. Biochemistry. 40: 11734-41
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