Emma H. Doud, Ph.D.
Affiliations: | 2011 | Harvard University, Cambridge, MA, United States |
Area:
molecular mechanisms of various antibioticsGoogle:
"Emma Doud"Mean distance: 8.43 | S | N | B | C | P |
Parents
Sign in to add mentorDaniel E. Kahne | grad student | 2011 | Harvard | |
(The genetics and biochemistry of moenomycin biosynthesis.) |
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Publications
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Makitrynskyy R, Ostash B, Tsypik O, et al. (2013) Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin. Open Biology. 3: 130121 |
Gampe CM, Tsukamoto H, Doud EH, et al. (2013) Tuning the moenomycin pharmacophore to enable discovery of bacterial cell wall synthesis inhibitors. Journal of the American Chemical Society. 135: 3776-9 |
Lupoli TJ, Tsukamoto H, Doud EH, et al. (2011) Transpeptidase-mediated incorporation of D-amino acids into bacterial peptidoglycan. Journal of the American Chemical Society. 133: 10748-51 |
Doud EH, Perlstein DL, Wolpert M, et al. (2011) Two distinct mechanisms for TIM barrel prenyltransferases in bacteria. Journal of the American Chemical Society. 133: 1270-3 |
Ostash B, Doud E, Fedorenko V. (2010) The molecular biology of moenomycins: towards novel antibiotics based on inhibition of bacterial peptidoglycan glycosyltransferases. Biological Chemistry. 391: 499-504 |
Perlstein DL, Wang TS, Doud EH, et al. (2010) The role of the substrate lipid in processive glycan polymerization by the peptidoglycan glycosyltransferases. Journal of the American Chemical Society. 132: 48-9 |
Ostash B, Doud EH, Lin C, et al. (2009) Complete characterization of the seventeen step moenomycin biosynthetic pathway. Biochemistry. 48: 8830-41 |