Joshua I. Armstrong, Ph.D.
Affiliations: | 2001 | University of California, Berkeley, Berkeley, CA, United States |
Area:
Bioorthogonal chemistryGoogle:
"Joshua Armstrong"Mean distance: 8.32 | S | N | B | C | P |
Parents
Sign in to add mentor| Carolyn R. Bertozzi | grad student | 2001 | UC Berkeley | |
| (The synthesis and biochemical evaluation of sulfotransferase inhibitors.) | ||||
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Publications
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| Armstrong JI, Verdugo DE, Bertozzi CR. (2003) Synthesis of a bisubstrate analogue targeting estrogen sulfotransferase. The Journal of Organic Chemistry. 68: 170-3 |
| Pi N, Armstrong JI, Bertozzi CR, et al. (2002) Kinetic analysis of NodST sulfotransferase using an electrospray ionization mass spectrometry assay. Biochemistry. 41: 13283-8 |
| Kehoe JW, Maly DJ, Verdugo DE, et al. (2002) Tyrosylprotein sulfotransferase inhibitors generated by combinatorial target-guided ligand assembly. Bioorganic & Medicinal Chemistry Letters. 12: 329-32 |
| Armstrong JI, Ge X, Verdugo DE, et al. (2001) A library approach to the generation of bisubstrate analogue sulfotransferase inhibitors. Organic Letters. 3: 2657-60 |
| Armstrong JI, Bertozzi CR. (2000) Sulfotransferases as targets for therapeutic intervention. Current Opinion in Drug Discovery & Development. 3: 502-15 |
| Saxon E, Armstrong JI, Bertozzi CR. (2000) A "traceless" Staudinger ligation for the chemoselective synthesis of amide bonds. Organic Letters. 2: 2141-3 |
| Armstrong JI, Portley AR, Chang YT, et al. (2000) Discovery of Carbohydrate Sulfotransferase Inhibitors from a Kinase-Directed Library We thank Sharon Long and Dave Keating for providing both the NodH sulfotransferase and APS Kinase during our preliminary experiments and Jack Kirsch for numerous helpful conversations. J.I.A. and K.G.B were supported by NIH Molecular Biophysics Training Grant (No. T32GM0895). This research was funded by grants to C.R.B. from the Pew Scholars Program, the W. M. Keck Foundation and the American Cancer Society (Grant No. RPG9700501BE). Angewandte Chemie (International Ed. in English). 39: 1303-1306 |
| Cook BN, Bhakta S, Biegel T, et al. (2000) Differential carbohydrate recognition of two GlcNAc-6-sulfotransferases with possible roles in L-selectin ligand biosynthesis Journal of the American Chemical Society. 122: 8612-8622 |