Michael W. Schelle, Ph.D.

Affiliations: 
2007 University of California, Berkeley, Berkeley, CA, United States 
Area:
Bioorthogonal chemistry
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"Michael Schelle"
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Carolyn R. Bertozzi grad student 2007 UC Berkeley
 (The contribution of sulfated metabolites to mycobacterial pathogenesis.)
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Publications

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Sharrar A, Meacham Z, Staples-Ager J, et al. (2024) Viral Delivery of Compact CRISPR-Cas12f for Gene Editing Applications. The Crispr Journal
Sharrar A, Arake de Tacca L, Meacham Z, et al. (2024) Discovery and engineering of AiEvo2, a novel Cas12a nuclease for human gene editing applications. The Journal of Biological Chemistry. 105685
Meacham Z, de Tacca LA, Bondy-Denomy J, et al. (2023) Cas9 degradation in human cells using phage anti-CRISPR proteins. Plos Biology. 21: e3002431
Sharrar A, Arake de Tacca L, Collingwood T, et al. (2023) Discovery and Characterization of Novel Type V Cas12f Nucleases with Diverse Protospacer Adjacent Motif Preferences. The Crispr Journal
Sogi KM, Gartner ZJ, Breidenbach MA, et al. (2013) Mycobacterium tuberculosis Rv3406 is a type II alkyl sulfatase capable of sulfate scavenging. Plos One. 8: e65080
Gilmore SA, Schelle MW, Holsclaw CM, et al. (2012) Sulfolipid-1 biosynthesis restricts Mycobacterium tuberculosis growth in human macrophages. Acs Chemical Biology. 7: 863-70
Seeliger JC, Holsclaw CM, Schelle MW, et al. (2012) Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis. The Journal of Biological Chemistry. 287: 7990-8000
Hatzios SK, Schelle MW, Newton GL, et al. (2011) The Mycobacterium tuberculosis CysQ phosphatase modulates the biosynthesis of sulfated glycolipids and bacterial growth. Bioorganic & Medicinal Chemistry Letters. 21: 4956-9
Crimmins GT, Schelle MW, Herskovits AA, et al. (2009) Listeria monocytogenes 6-Phosphogluconolactonase mutants induce increased activation of a host cytosolic surveillance pathway. Infection and Immunity. 77: 3014-22
Hatzios SK, Schelle MW, Holsclaw CM, et al. (2009) PapA3 is an acyltransferase required for polyacyltrehalose biosynthesis in Mycobacterium tuberculosis. The Journal of Biological Chemistry. 284: 12745-51
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