Jorge Becerril, Ph.D.
Affiliations: | 2007 | Yale University, New Haven, CT |
Area:
chemical biologyGoogle:
"Jorge Becerril"Mean distance: 8.23 | S | N | B | C | P |
Parents
Sign in to add mentor| Andrew D. Hamilton | grad student | 2007 | Yale | |
| (Development of functional alpha-helix mimetics.) | ||||
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Publications
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| Kazi A, Sun J, Doi K, et al. (2011) The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner. The Journal of Biological Chemistry. 286: 9382-92 |
| Saraogi I, Hebda JA, Becerril J, et al. (2010) Synthetic alpha-helix mimetics as agonists and antagonists of islet amyloid polypeptide aggregation. Angewandte Chemie (International Ed. in English). 49: 736-9 |
| Becerril J, Rodriguez JM, Wyrembak PN, et al. (2010) Inhibition of Protein-Protein Interactions by Peptide Mimics Protein Surface Recognition: Approaches For Drug Discovery. 105-131 |
| Becerril J, Hamilton AD. (2007) Helix mimetics as inhibitors of the interaction of the estrogen receptor with coactivator peptides. Angewandte Chemie (International Ed. in English). 46: 4471-3 |
| Ernst JT, Becerril J, Park HS, et al. (2003) Design and application of an alpha-helix-mimetic scaffold based on an oligoamide-foldamer strategy: antagonism of the Bak BH3/Bcl-xL complex. Angewandte Chemie (International Ed. in English). 42: 535-9 |