Richard S. Agnes, Ph.D.
Affiliations: | 2003 | University of Arizona, Tucson, AZ |
Area:
Organic Chemistry, Biochemistry, Chemical Biology and Medicinal ChemistryGoogle:
"Richard Agnes"Mean distance: 10.67 | S | N | B | C | P |
Parents
Sign in to add mentor| Victor J. Hruby | grad student | 2003 | University of Arizona | |
| (New paradigm for drug design: Design and synthesis of novel biologically active peptides that are agonists at opioid receptors and antagonists at cholecystokinin receptors.) | ||||
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Publications
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| Agnes RS, Broome AM, Wang J, et al. (2012) An optical probe for noninvasive molecular imaging of orthotopic brain tumors overexpressing epidermal growth factor receptor. Molecular Cancer Therapeutics. 11: 2202-11 |
| Hanlon KE, Herman DS, Agnes RS, et al. (2011) Novel peptide ligands with dual acting pharmacophores designed for the pathophysiology of neuropathic pain. Brain Research. 1395: 1-11 |
| Broome A, Lavik K, Ramamurthy G, et al. (2010) Abstract 4341: Tumor imaging via β-galactosidase fragment complementation with a multifunctional targeted-reporter complex Cancer Research. 70: 4341-4341 |
| Zhang W, Gardell S, Zhang D, et al. (2009) Neuropathic pain is maintained by brainstem neurons co-expressing opioid and cholecystokinin receptors. Brain : a Journal of Neurology. 132: 778-87 |
| Agnes RS, Ying J, Kövér KE, et al. (2008) Structure-activity relationships of bifunctional cyclic disulfide peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors. Peptides. 29: 1413-23 |
| Lee YS, Agnes RS, Cain JP, et al. (2008) Opioid and melanocortin receptors: do they have overlapping pharmacophores? Biopolymers. 90: 433-8 |
| Nandy SK, Agnes RS, Lawrence DS. (2007) Photochemically-activated probes of protein-protein interactions. Organic Letters. 9: 2249-52 |
| Lee YS, Nyberg J, Moye S, et al. (2007) Understanding the structural requirements of 4-anilidopiperidine analogues for biological activities at mu and delta opioid receptors. Bioorganic & Medicinal Chemistry Letters. 17: 2161-5 |
| Lee YS, Agnes RS, Davis P, et al. (2007) Partial retro-inverso, retro, and inverso modifications of hydrazide linked bifunctional peptides for opioid and cholecystokinin (CCK) receptors. Journal of Medicinal Chemistry. 50: 165-8 |
| Hruby VJ, Porreca F, Yamamura HI, et al. (2006) New paradigms and tools in drug design for pain and addiction. The Aaps Journal. 8: E450-60 |