☰

James Cain, Ph.D.

Affiliations: 
2011 Chemistry University of Arizona, Tucson, AZ 
Area:
Organic Chemistry, Biochemistry, Chemical Biology and Medicinal Chemistry
Google:
"James Cain"
Mean distance: 10.67
 		SNBCP
Tree Publications Similar researchers PubMed Report error

Parents

Sign in to add mentor
Victor J. Hruby grad student 2011 University of Arizona
 (Design, synthesis, and evaluation of new ligands for G Protein-Coupled Receptors (GPCRs) and kinases.)

Children

Sign in to add trainee

Collaborators

Sign in to add collaborator
BETA: Related publications

Publications

You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect.

Vardanyan RS, Cain JP, Haghighi SM, et al. (2017) Synthesis and Investigation of Mixed μ-Opioid and δ-Opioid Agonists as Possible Bivalent Ligands for Treatment of Pain. Journal of Heterocyclic Chemistry. 54: 1228-1235
Podolsky AT, Sandweiss A, Hu J, et al. (2013) Novel fentanyl-based dual μ/δ-opioid agonists for the treatment of acute and chronic pain. Life Sciences. 93: 1010-6
Mayorov AV, Cai M, Palmer ES, et al. (2011) Cyclic lactam hybrid α-MSH/Agouti-related protein (AGRP) analogues with nanomolar range binding affinities at the human melanocortin receptors. Bioorganic & Medicinal Chemistry Letters. 21: 3099-102
Hruby VJ, Cai M, Cain J, et al. (2011) Design of novel melanocortin receptor ligands: multiple receptors, complex pharmacology, the challenge. European Journal of Pharmacology. 660: 88-93
Mayorov AV, Cai M, Palmer ES, et al. (2010) Solid-phase peptide head-to-side chain cyclodimerization: discovery of C(2)-symmetric cyclic lactam hybrid α-melanocyte-stimulating hormone (MSH)/agouti-signaling protein (ASIP) analogues with potent activities at the human melanocortin receptors. Peptides. 31: 1894-905
Mayorov AV, Cai M, Palmer ES, et al. (2008) Structure-activity relationships of cyclic lactam analogues of alpha-melanocyte-stimulating hormone (alpha-MSH) targeting the human melanocortin-3 receptor. Journal of Medicinal Chemistry. 51: 187-95
Lee YS, Agnes RS, Cain JP, et al. (2008) Opioid and melanocortin receptors: do they have overlapping pharmacophores? Biopolymers. 90: 433-8
Hruby VJ, Cai M, Cain JP, et al. (2007) Design, synthesis and biological evaluation of ligands selective for the melanocortin-3 receptor. Current Topics in Medicinal Chemistry. 7: 1107-19
Ndungu JM, Cain JP, Davis P, et al. (2006) Synthesis of constrained analogues of cholecystokinin/opioid chimeric peptides. Tetrahedron Letters. 47: 2233-2236
Cain JP, Mayorov AV, Cai M, et al. (2006) Design, synthesis, and biological evaluation of a new class of small molecule peptide mimetics targeting the melanocortin receptors. Bioorganic & Medicinal Chemistry Letters. 16: 5462-7
See more...