Brian B. Liau, Ph.D.
Affiliations: | 2013 | Chemistry and Chemical Biology | Harvard University, Cambridge, MA, United States |
Area:
Organic synthesisGoogle:
"Brian Liau"Mean distance: 7.73 | S | N | B | C | P |
Parents
Sign in to add mentor| Elias James Corey | research assistant | Harvard | ||
| Matthew D. Shair | grad student | 2013 | Harvard | |
| (Total syntheses of fastigiatine and the hibarimicin aglycons.) | ||||
| Bradley E. Bernstein | post-doc | Harvard Medical School (Cell Biology Tree) | ||
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Publications
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| Ngan KC, Hoenig SM, Kwok HS, et al. (2023) Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery. Elife. 12 |
| Najm FJ, DeWeirdt P, Moore MM, et al. (2023) Chromatin complex dependencies reveal targeting opportunities in leukemia. Nature Communications. 14: 448 |
| Gosavi PM, Ngan KC, Yeo MJR, et al. (2022) Profiling the Landscape of Drug Resistance Mutations in Neosubstrates to Molecular Glue Degraders. Acs Central Science. 8: 417-429 |
| Kato S, Weng QY, Insco ML, et al. (2020) Gain-of-function genetic alterations of G9a drive oncogenesis. Cancer Discovery |
| Siegenfeld AP, Lee C, Liau BB. (2019) Taking a STAP at Core Promoter-Transcriptional Cofactor Specificity. Biochemistry |
| Vinyard ME, Su C, Siegenfeld AP, et al. (2019) CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML. Nature Chemical Biology. 15: 529-539 |
| Park Y, Koga Y, Su C, et al. (2019) A Versatile Synthetic Route to Cycloheximide and Analogues that Potently Inhibit Translation Elongation. Angewandte Chemie (International Ed. in English) |
| Miller TE, Liau BB, Wallace LC, et al. (2017) Transcription elongation factors represent in vivo cancer dependencies in glioblastoma. Nature |
| Miller TE, Liau B, Wallace LC, et al. (2017) GENE-30. TRANSCRIPTION ELONGATION FACTORS REPRESENT IN VIVO CANCER DEPENDENCIES IN GLIOBLASTOMA Neuro-Oncology. 19: vi99-vi99 |
| Liau BB, Sievers C, Donohue LK, et al. (2016) Adaptive Chromatin Remodeling Drives Glioblastoma Stem Cell Plasticity and Drug Tolerance. Cell Stem Cell |