Sarah D. Cady, Ph.D.
Affiliations: | 2009 | Chemistry | Iowa State University, Ames, IA, United States |
Area:
solid-state NMR spectroscopy to investigate the structure and dynamics of membrane proteins and fibrous proteinsGoogle:
"Sarah Cady"Mean distance: 9.9 | S | N | B | C | P |
Parents
Sign in to add mentor| Mei Hong | grad student | 2009 | Iowa State | |
| (Investigation of the structure and dynamics of the M2 transmembrane peptide of the influenza A virus by solid-state nuclear magnetic resonance.) | ||||
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Publications
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| Wang T, Cady SD, Hong M. (2012) NMR determination of protein partitioning into membrane domains with different curvatures and application to the influenza M2 peptide. Biophysical Journal. 102: 787-94 |
| Cady S, Wang T, Hong M. (2011) Membrane-dependent effects of a cytoplasmic helix on the structure and drug binding of the influenza virus M2 protein. Journal of the American Chemical Society. 133: 11572-9 |
| Cady SD, Wang J, Wu Y, et al. (2011) Specific binding of adamantane drugs and direction of their polar amines in the pore of the influenza M2 transmembrane domain in lipid bilayers and dodecylphosphocholine micelles determined by NMR spectroscopy. Journal of the American Chemical Society. 133: 4274-84 |
| Hu F, Luo W, Cady SD, et al. (2011) Conformational plasticity of the influenza A M2 transmembrane helix in lipid bilayers under varying pH, drug binding, and membrane thickness. Biochimica Et Biophysica Acta. 1808: 415-23 |
| Cady SD, Schmidt-Rohr K, Wang J, et al. (2010) Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers. Nature. 463: 689-92 |
| Cady S, Schmidt-Rohr K, Wang J, et al. (2010) Solid-state NMR structure of the M2 transmembrane peptide of the influenza A virus in DMPC lipid bilayers bound to deuterated amantadine Journal of Back and Musculoskeletal Rehabilitation |
| Cady SD, Hong M. (2009) Effects of amantadine on the dynamics of membrane-bound influenza A M2 transmembrane peptide studied by NMR relaxation. Journal of Biomolecular Nmr. 45: 185-96 |
| Cady SD, Luo W, Hu F, et al. (2009) Structure and function of the influenza A M2 proton channel. Biochemistry. 48: 7356-64 |
| Luo W, Cady SD, Hong M. (2009) Immobilization of the influenza A M2 transmembrane peptide in virus envelope-mimetic lipid membranes: a solid-state NMR investigation. Biochemistry. 48: 6361-8 |
| Wang J, Cady SD, Balannik V, et al. (2009) Discovery of spiro-piperidine inhibitors and their modulation of the dynamics of the M2 proton channel from influenza A virus. Journal of the American Chemical Society. 131: 8066-76 |