Ivar M. McDonald, Ph.D.
Affiliations: | 2005 | Yale University, New Haven, CT |
Area:
natural product synthesisGoogle:
"Ivar McDonald"Mean distance: 8.18 | S | N | B | C | P |
Parents
Sign in to add mentor| John Louis Wood | grad student | 2005 | Yale | |
| (Progress toward the total synthesis of the Phomoidrides.) | ||||
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Publications
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| Knouse KW, deGruyter JN, Schmidt MA, et al. (2018) Unlocking P(V): Reagents for chiral phosphorothioate synthesis. Science (New York, N.Y.) |
| Jarugu LB, Reddy CA, Chikkananjunda NK, et al. (2018) Process Optimization for the Large-Scale Preparation of (2S,3aR,7aS)-tert-Butyl Hexahydro-2,5-methanopyrrolo[3,2-c]pyridine-1(4H)-carboxylate, an Intermediate for Nicotinic Acetylcholine Receptor Agonists Organic Process Research & Development. 22: 1276-1281 |
| McDonald IM, Ng A, Cutrone J, et al. (2018) Novel tricyclic diamines 1. Synthesis of 1,4-diazaisotwistane and 1,4-diazahomoisotwistane as constrained 3-aminoquinuclidine isosteres Tetrahedron Letters. 59: 747-750 |
| McDonald IM, Ng A. (2018) Novel tricyclic diamines 3. Synthesis of 1,4-diazaadamantane Tetrahedron Letters. 59: 755-759 |
| McDonald IM, Mate R, Ng A, et al. (2018) Novel tricyclic diamines 2. Synthesis of 1,7-diazaisoadamantane, 1,5-diazaisoadamantane and 1,6-diazahomobrendane Tetrahedron Letters. 59: 751-754 |
| Leung JC, Bedermann AA, Njardarson JT, et al. (2017) Total Synthesis of (±)-Phomoidride D. Angewandte Chemie (International Ed. in English) |
| Cook J, Zusi FC, Hill MD, et al. (2017) Design and synthesis of a novel series of (1'S,2R,4'S)-3H-4'-azaspiro[benzo[4,5]imidazo[2,1-b]oxazole-2,2'-bicyclo[2.2.2]octanes] with high affinity for the α7 neuronal nicotinic receptor. Bioorganic & Medicinal Chemistry Letters |
| Iwuagwu C, King D, McDonald IM, et al. (2017) Design and synthesis of a novel series of 4-heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes as α7 nicotinic receptor agonists 2. Development of 4-heteroaryl SAR. Bioorganic & Medicinal Chemistry Letters |
| Hill MD, Fang H, King HD, et al. (2017) Development of 4-Heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes] as α7 Nicotinic Receptor Agonists. Acs Medicinal Chemistry Letters. 8: 133-137 |
| Cook J, Zusi FC, McDonald IM, et al. (2016) Design and Synthesis of a New Series of 4-Heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes as α7 Nicotinic Receptor Agonists. 1. Development of Pharmacophore and Early Structure-Activity Relationship. Journal of Medicinal Chemistry |