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Jason E. Donald, Ph.D.

Affiliations: 
2007 Harvard University, Cambridge, MA, United States 
Area:
Protein Folding and Design, Molecular Evolution, Drug Discovery
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Eugene I. Shakhnovich grad student 2007 Harvard
 (The specificity of protein -DNA interactions.)

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Schramm CA, Hannigan BT, Donald JE, et al. (2012) Knowledge-based potential for positioning membrane-associated structures and assessing residue-specific energetic contributions. Structure (London, England : 1993). 20: 924-35
Kim YH, Donald JE, Grigoryan G, et al. (2011) Capture and imaging of a prehairpin fusion intermediate of the paramyxovirus PIV5. Proceedings of the National Academy of Sciences of the United States of America. 108: 20992-7
Donald JE, Zhang Y, Fiorin G, et al. (2011) Transmembrane orientation and possible role of the fusogenic peptide from parainfluenza virus 5 (PIV5) in promoting fusion. Proceedings of the National Academy of Sciences of the United States of America. 108: 3958-63
Donald JE, Kulp DW, DeGrado WF. (2011) Salt bridges: geometrically specific, designable interactions. Proteins. 79: 898-915
Fiorin G, Donald JE, Zhang Y, et al. (2011) Association of Transmembrane Helices in Viral Fusion Peptides Suggests a Protein-Centric Mechanism of Membrane Fusion Biophysical Journal. 100: 633a
Donald JE, Zhu H, Litvinov RI, et al. (2010) Identification of interacting hot spots in the beta3 integrin stalk using comprehensive interface design. The Journal of Biological Chemistry. 285: 38658-65
Bissonnette ML, Donald JE, DeGrado WF, et al. (2009) Functional analysis of the transmembrane domain in paramyxovirus F protein-mediated membrane fusion. Journal of Molecular Biology. 386: 14-36
Donald JE, Shakhnovich EI. (2009) SDR: a database of predicted specificity-determining residues in proteins. Nucleic Acids Research. 37: D191-4
Donald JE, Zhu H, DeGrado WF, et al. (2009) Identification of Stalk Mutations That Stabilize the High Affinity Conformation of αIIbβ3 by Negative Design. Blood. 114: 4017-4017
Donald JE, Chen WW, Shakhnovich EI. (2007) Energetics of protein-DNA interactions. Nucleic Acids Research. 35: 1039-47
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