Peter S. Kutchukian, Ph.D.
Affiliations: | 2010 | Harvard University, Cambridge, MA, United States |
Area:
Protein Folding and Design, Molecular Evolution, Drug DiscoveryGoogle:
"Peter Kutchukian"Mean distance: 8.94 | S | N | B | C | P |
Parents
Sign in to add mentorEugene I. Shakhnovich | grad student | 2010 | Harvard | |
(Computational and experimental investigation of ligand design.) |
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Publications
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Lam PY, Kutchukian P, Anand R, et al. (2020) Cyp1 inhibition prevents doxorubicin-induced cardiomyopathy in a zebrafish heart failure model. Chembiochem : a European Journal of Chemical Biology |
Kutchukian PS, Chang C, Fox SJ, et al. (2017) CHEMGENIE: integration of chemogenomics data for applications in chemical biology. Drug Discovery Today |
Santa Maria JP, Park Y, Yang L, et al. (2017) Linking High-Throughput Screens to Identify MoAs and Novel Inhibitors of Mycobacterium tuberculosis Dihydrofolate Reductase. Acs Chemical Biology |
Pertusi DA, O'Donnell G, Homsher MF, et al. (2017) Prospective Assessment of Virtual Screening Heuristics Derived Using a Novel Fusion Score. Slas Discovery. 2472555217706058 |
Filzen TM, Kutchukian PS, Hermes JD, et al. (2017) Representing high throughput expression profiles via perturbation barcodes reveals compound targets. Plos Computational Biology. 13: e1005335 |
Kutchukian PS, Dropinski JF, Dykstra KD, et al. (2016) Chemistry informer libraries: a chemoinformatics enabled approach to evaluate and advance synthetic methods. Chemical Science. 7: 2604-2613 |
Kutchukian PS, Warren L, Magliaro BC, et al. (2016) Iterative Focused Screening with Biological Fingerprints Identifies Selective Asc-1 Inhibitors Distinct from Traditional High Throughput Screening. Acs Chemical Biology |
Greshock TJ, Moore KP, McClain RT, et al. (2016) Synthesis of Complex Druglike Molecules by the Use of Highly Functionalized Bench-Stable Organozinc Reagents. Angewandte Chemie (International Ed. in English) |
Kutchukian PS, So SS, Fischer C, et al. (2015) Fragment library design: using cheminformatics and expert chemists to fill gaps in existing fragment libraries. Methods in Molecular Biology (Clifton, N.J.). 1289: 43-53 |
Kutchukian PS, Wassermann AM, Lindvall MK, et al. (2015) Large scale meta-analysis of fragment-based screening campaigns: privileged fragments and complementary technologies. Journal of Biomolecular Screening. 20: 588-96 |