Melissa A. Mefford, Ph.D.
Affiliations: | 2009 | University of Chicago, Chicago, IL |
Area:
mRNA processingGoogle:
"Melissa Mefford"Mean distance: 11.6 | S | N | B | C | P |
Parents
Sign in to add mentor| Jon Staley | grad student | 2009 | Chicago | |
| (snRNA structure and dynamics during the catalytic phase of pre -mRNA splicing.) | ||||
| David C. Zappulla | grad student | 2016 | Johns Hopkins (Telomere and Telomerase Tree) | |
| (Postdoc) | ||||
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Publications
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| Mefford MA, Hass EP, Zappulla DC. (2020) A 4-base pair core-enclosing helix in telomerase RNA is essential for activity and for binding to the TERT catalytic protein subunit. Molecular and Cellular Biology |
| Mefford MA, Zappulla DC. (2015) Physical connectivity mapping by circular permutation of human telomerase RNA reveals new regions critical for activity and processivity. Molecular and Cellular Biology |
| Fica SM, Mefford MA, Piccirilli JA, et al. (2014) Evidence for a group II intron-like catalytic triplex in the spliceosome. Nature Structural & Molecular Biology. 21: 464-71 |
| Mefford MA, Rafiq Q, Zappulla DC. (2013) RNA connectivity requirements between conserved elements in the core of the yeast telomerase RNP. The Embo Journal. 32: 2980-93 |
| Mefford MA, Staley JP. (2009) Evidence that U2/U6 helix I promotes both catalytic steps of pre-mRNA splicing and rearranges in between these steps. Rna (New York, N.Y.). 15: 1386-97 |
| Hilliker AK, Mefford MA, Staley JP. (2007) U2 toggles iteratively between the stem IIa and stem IIc conformations to promote pre-mRNA splicing. Genes & Development. 21: 821-34 |