Jason J. Reddick, Ph.D.
Affiliations: | 2001 | Cornell University, Ithaca, NY, United States |
Area:
Barton Professor of ChemistryGoogle:
"Jason Reddick"Mean distance: 8.55 | S | N | B | C | P |
Parents
Sign in to add mentor| Tadhg P. Begley | grad student | 2001 | Cornell | |
| (Mechanistic studies on thiamin phosphate synthase from Bacillus subtilis.) | ||||
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Publications
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| Melnick JS, Sprinz KI, Reddick JJ, et al. (2003) An efficient enzymatic synthesis of thiamin pyrophosphate. Bioorganic & Medicinal Chemistry Letters. 13: 4139-41 |
| Reddick JJ, Saha S, Lee J, et al. (2001) The mechanism of action of bacimethrin, a naturally occurring thiamin antimetabolite. Bioorganic & Medicinal Chemistry Letters. 11: 2245-8 |
| Peapus DH, Chiu HJ, Campobasso N, et al. (2001) Structural characterization of the enzyme-substrate, enzyme-intermediate, and enzyme-product complexes of thiamin phosphate synthase. Biochemistry. 40: 10103-14 |
| Reddick JJ, Nicewonger R, Begley TP. (2001) Mechanistic studies on thiamin phosphate synthase: evidence for a dissociative mechanism. Biochemistry. 40: 10095-102 |
| Begley TP, Downs DM, Ealick SE, et al. (1999) Thiamin biosynthesis in prokaryotes. Archives of Microbiology. 171: 293-300 |
| Chiu HJ, Reddick JJ, Begley TP, et al. (1999) Crystal structure of thiamin phosphate synthase from Bacillus subtilis at 1.25 A resolution. Biochemistry. 38: 6460-70 |
| Reddick JJ, Kinsland C, Nicewonger R, et al. (1998) Overexpression, purification and characterization of two pyrimidine kinases involved in the biosynthesis of thiamin: 4-amino-5-hydroxymethyl-2- methylpyrimidine kinase and 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase Tetrahedron. 54: 15983-15991 |
| Begley TP, Campobasso N, Costello C, et al. (1998) Mechanistic studies on thiamin formation and degradation: Thiaminase I and thiamin phosphate synthase Faseb Journal. 12: A1331 |