Erick Strauss, Ph.D.

Affiliations: 
2003 Cornell University, Ithaca, NY, United States 
Area:
Barton Professor of Chemistry
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"Erick Strauss"
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Tadhg P. Begley grad student 2003 Cornell
 (Thiols, radicals and antibiotics: Mechanistic studies in coenzyme A biosynthesis.)
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Publications

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Alkhalaf LM, Arrowsmith C, Balskus EP, et al. (2024) Thoughts for the future. Nature Chemical Biology. 21: 6-15
Mostert KJ, Sharma N, van der Zwaag M, et al. (2021) The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity. Acs Chemical Biology
Spry C, Barnard L, Kok M, et al. (2020) Towards a stable and potent coenzyme A-targeting antiplasmodial agent: structure-activity relationship studies of N-phenethyl-α-methyl-pantothenamide. Acs Infectious Diseases
Sharma N, Ahalawat N, Sandhu P, et al. (2020) Role of allosteric switches and adaptor domains in long-distance cross-talk and transient tunnel formation. Science Advances. 6: eaay7919
Domingo R, van der Westhuyzen R, Hamann AR, et al. (2019) Overcoming synthetic challenges in targeting coenzyme A biosynthesis with the antimicrobial natural product CJ-15,801. Medchemcomm. 10: 2118-2125
Guan J, Barnard L, Cresson J, et al. (2018) Probing the ligand preferences of the three types of bacterial pantothenate kinase. Bioorganic & Medicinal Chemistry
Santolaria C, Velázquez D, Strauss E, et al. (2018) Mutations at the hydrophobic core affect Hal3 trimer stability, reducing its Ppz1 inhibitory capacity but not its PPCDC moonlighting function. Scientific Reports. 8: 14701
Tjhin ET, Spry C, Sewell AL, et al. (2018) Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues. Plos Pathogens. 14: e1006918
Barnard L, Mostert KJ, van Otterlo WAL, et al. (2018) Developing Pantetheinase-Resistant Pantothenamide Antibacterials: Structural Modification Impacts on PanK Interaction and Mode of Action. Acs Infectious Diseases
de Villiers M, Spry C, Macuamule CJ, et al. (2017) Antiplasmodial mode of action of pantothenamides: pantothenate kinase serves as a metabolic activator, not as a target. Acs Infectious Diseases
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