Patrick M. O'Donoghue, Ph.D.

Affiliations: 
2004 University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
Area:
Prediction of Protein Structure and Function
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"Patrick O'Donoghue"
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Zaida A. Luthey-Schulten grad student 2004 UIUC
 (Evolution of protein structure.)
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Publications

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Ward C, Beharry A, Tennakoon R, et al. (2024) Mechanisms and Delivery of tRNA Therapeutics. Chemical Reviews
Davey-Young J, Hasan F, Tennakoon R, et al. (2024) Mistranslating the genetic code with leucine in yeast and mammalian cells. Rna Biology. 21: 1-23
Hasan F, Lant JT, O'Donoghue P. (2023) Perseverance of protein homeostasis despite mistranslation of glycine codons with alanine. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 378: 20220029
Guo LT, Amikura K, Jiang HK, et al. (2022) Ancestral Archaea Expanded the Genetic Code with Pyrrolysine. The Journal of Biological Chemistry. 102521
Balasuriya N, Davey NE, Johnson JL, et al. (2020) Phosphorylation-dependent substrate selectivity of protein kinase B (AKT1). The Journal of Biological Chemistry
Berg MD, Giguere DJ, Dron JS, et al. (2019) Targeted sequencing reveals expanded genetic diversity of human transfer RNAs. Rna Biology. 1-12
Lant JT, Berg MD, Heinemann IU, et al. (2019) Pathways to disease from natural variations in human cytoplasmic tRNAs. The Journal of Biological Chemistry
Balasuriya N, Kunkel MT, Liu X, et al. (2018) Genetic code expansion and live cell imaging reveal that Thr308 phosphorylation is irreplaceable and sufficient for Akt1 activity. The Journal of Biological Chemistry
Wright D, Altaany Z, Bi Y, et al. (2017) Acetylation regulates thioredoxin reductase oligomerization and activity. Antioxidants & Redox Signaling
Lant JT, Berg MD, Sze DH, et al. (2017) Visualizing tRNA-dependent mistranslation in human cells. Rna Biology. 0
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