Robert H. Dowen, Ph.D.

Affiliations: 
2009 Biomedical Sciences University of California, San Diego, La Jolla, CA 
Area:
Protein Tyrosine Phosphatase, Dual=specific Phosphatase, PTEN
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Parents

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Jack E. Dixon grad student 2009 UCSD
 (Dynamics of the plant -pathogen interaction: Strategies for bacterial virulence and coordinating the plant defense response.)
Joseph R. Ecker post-doc Assistant Professor, Biology Department, University of North Carolina (Plant Biology Tree)
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Publications

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Dowen RH, Ahmed S. (2019) Maternal Inheritance: Longevity Programs Nourish Progeny via Yolk. Current Biology : Cb. 29: R748-R751
Dowen RH. (2019) CEH-60/PBX and UNC-62/MEIS Coordinate a Metabolic Switch that Supports Reproduction in C. elegans. Developmental Cell
Dowen RH, Breen PC, Tullius T, et al. (2016) A microRNA program in the C. elegans hypodermis couples to intestinal mTORC2/PQM-1 signaling to modulate fat transport. Genes & Development. 30: 1515-28
Cheesman HK, Feinbaum RL, Thekkiniath J, et al. (2016) Aberrant Activation of p38 MAP Kinase-Dependent Innate Immune Responses is Toxic to Caenorhabditis elegans. G3 (Bethesda, Md.)
Qi D, Dubiella U, Kim SH, et al. (2014) Recognition of the protein kinase AVRPPHB SUSCEPTIBLE1 by the disease resistance protein RESISTANCE TO PSEUDOMONAS SYRINGAE5 is dependent on s-acylation and an exposed loop in AVRPPHB SUSCEPTIBLE1. Plant Physiology. 164: 340-51
Riedel CG, Dowen RH, Lourenco GF, et al. (2013) DAF-16 employs the chromatin remodeller SWI/SNF to promote stress resistance and longevity. Nature Cell Biology. 15: 491-501
Dowen RH, Pelizzola M, Schmitz RJ, et al. (2012) Widespread dynamic DNA methylation in response to biotic stress. Proceedings of the National Academy of Sciences of the United States of America. 109: E2183-91
Montgomery TA, Rim YS, Zhang C, et al. (2012) PIWI associated siRNAs and piRNAs specifically require the Caenorhabditis elegans HEN1 ortholog henn-1. Plos Genetics. 8: e1002616
Lister R, Pelizzola M, Dowen RH, et al. (2009) Human DNA methylomes at base resolution show widespread epigenomic differences. Nature. 462: 315-22
Dowen RH, Engel JL, Shao F, et al. (2009) A family of bacterial cysteine protease type III effectors utilizes acylation-dependent and -independent strategies to localize to plasma membranes. The Journal of Biological Chemistry. 284: 15867-79
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