Christopher W. McAndrew, Ph.D.

Affiliations: 
2010 Chemistry University of California, San Diego, La Jolla, CA 
Area:
Fibroblast Growth Factor Receptors (FGFRs) in Human Cancer
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"Christopher McAndrew"
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Daniel J. Donoghue grad student 2010 UCSD
 (Cell cycle and DNA damage response regulation by Spy1, and the intersection of FGFR and NFkappaB pathways.)
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Publications

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Meyer AN, Drafahl KA, McAndrew CW, et al. (2013) Tyrosine phosphorylation allows integration of multiple signaling inputs by IKKβ. Plos One. 8: e84497
Fleming JM, Ginsburg E, McAndrew C, et al. (2013) Abstract 528: Characterization of Δ7/11, a functional prolactin-binding protein. Cancer Research. 73: 528-528
McAndrew C, Heger C, Saab A, et al. (2013) Abstract 3208: Development of applications for acoustic membrane microparticle assay technology for translational medicine. Cancer Research. 73: 3208-3208
Drafahl KA, McAndrew CW, Meyer AN, et al. (2010) The receptor tyrosine kinase FGFR4 negatively regulates NF-kappaB signaling. Plos One. 5: e14412
Drafahl KA, McAndrew CW, Donoghue DJ. (2010) Signaling from fibroblast growth factor receptors in development and disease Handbook of Cell Signaling, 2/E. 2: 1939-1947
McAndrew CW, Gastwirt RF, Donoghue DJ. (2009) The atypical CDK activator Spy1 regulates the intrinsic DNA damage response and is dependent upon p53 to inhibit apoptosis. Cell Cycle (Georgetown, Tex.). 8: 66-75
Meyer AN, McAndrew CW, Donoghue DJ. (2008) Nordihydroguaiaretic acid inhibits an activated fibroblast growth factor receptor 3 mutant and blocks downstream signaling in multiple myeloma cells. Cancer Research. 68: 7362-70
McAndrew CW, Gastwirt RF, Meyer AN, et al. (2007) Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27. Cell Cycle (Georgetown, Tex.). 6: 1937-45
Gastwirt RF, McAndrew CW, Donoghue DJ. (2007) Speedy/RINGO regulation of CDKs in cell cycle, checkpoint activation and apoptosis. Cell Cycle (Georgetown, Tex.). 6: 1188-93
Gastwirt RF, Slavin DA, McAndrew CW, et al. (2006) Spy1 expression prevents normal cellular responses to DNA damage: inhibition of apoptosis and checkpoint activation. The Journal of Biological Chemistry. 281: 35425-35
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