Junan Li, Ph.D.

Affiliations: 
2000 Ohio State University, Columbus, Columbus, OH 
Area:
Protein Structure-Function, NMR, Enzyme Mechanism
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"Junan Li"
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Ming-Daw Tsai grad student 2000 Ohio State
 (Structural and functional studies on tumor suppressor INK4 proteins p16('INK4A) and p18('INK4C).)
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Publications

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Poi MJ, Knobloch TJ, Li J. (2017) Deletion of RD(INK4/ARF) enhancer: A novel mutation to "inactivate" the INK4-ARF locus. Dna Repair. 57: 50-55
Poi MJ, Li J, Sborov DW, et al. (2017) Polymorphism in ANRIL is associated with relapse in patients with multiple myeloma after autologous stem cell transplant. Molecular Carcinogenesis
Poi MJ, Knobloch TJ, Sears MT, et al. (2015) Alterations in RD(INK4/ARF) -mediated en bloc regulation of the INK4-ARF locus in human squamous cell carcinoma of the head and neck. Molecular Carcinogenesis. 54: 532-42
Poi MJ, Drosdeck J, Frankel WL, et al. (2014) Deletions of RDINK4/ARF enhancer in gastrinomas and nonfunctioning pancreatic neuroendocrine tumors. Pancreas. 43: 1009-13
Li J, Knobloch TJ, Poi MJ, et al. (2014) Genetic alterations of RD(INK4/ARF) enhancer in human cancer cells. Molecular Carcinogenesis. 53: 211-8
Yuan C, Guo Y, Zhu L, et al. (2013) The study of pH-dependent stability shows that the TPLH-mediated hydrogen-bonding network is important for the conformation and stability of human gankyrin. Biochemistry. 52: 4848-57
Poi MJ, Knobloch TJ, Yuan C, et al. (2013) Evidence that P12, a specific variant of P16(INK4A), plays a suppressive role in human pancreatic carcinogenesis. Biochemical and Biophysical Research Communications. 436: 217-22
Li J, Poi MJ, Tsai MD. (2011) Regulatory mechanisms of tumor suppressor P16(INK4A) and their relevance to cancer. Biochemistry. 50: 5566-82
Li J, Guo Y. (2010) Gankyrin Oncoprotein: Structure, Function, and Involvement in Cancer. Current Chemical Biology. 4: 13-19
Guo Y, Yuan C, Tian F, et al. (2010) Contributions of conserved TPLH tetrapeptides to the conformational stability of ankyrin repeat proteins. Journal of Molecular Biology. 399: 168-81
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