Sophia N. Ononye, Ph.D.
Affiliations: | 2013 | University of Connecticut, Storrs, CT, United States |
Area:
X-Ray crystallography, Structural biology, Molecular modeling, Structure-based drug designGoogle:
"Sophia Ononye"Mean distance: 9.95
Parents
Sign in to add mentor| Amy Christine Anderson | grad student | 2013 | University of Connecticut | |
| (Towards the Development of Tropolone Natural Product Derivatives as Novel, Potent Anticancer Therapeutics that Selectively Target Histone Deacetylase (HDAC) Enzymes.) | ||||
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Publications
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| Ononye SN, Vanheyst MD, Giardina C, et al. (2014) Studies on the antiproliferative effects of tropolone derivatives in Jurkat T-lymphocyte cells. Bioorganic & Medicinal Chemistry. 22: 2188-93 |
| Ononye SN, VanHeyst MD, Oblak EZ, et al. (2013) Tropolones as lead-like natural products: the development of potent and selective histone deacetylase inhibitors. Acs Medicinal Chemistry Letters. 4: 757-61 |
| Pavlik CM, Wong CY, Ononye S, et al. (2013) Santacruzamate A, a potent and selective histone deacetylase inhibitor from the Panamanian marine cyanobacterium cf. Symploca sp. Journal of Natural Products. 76: 2026-33 |
| Ononye SN, van Heyst M, Falcone EM, et al. (2012) Toward isozyme-selective inhibitors of histone deacetylase as therapeutic agents for the treatment of cancer. Pharmaceutical Patent Analyst. 1: 207-21 |
| Viswanathan K, Ononye SN, Cooper HD, et al. (2012) Viridin analogs derived from steroidal building blocks. Bioorganic & Medicinal Chemistry Letters. 22: 6919-22 |
| Oblak EZ, Bolstad ES, Ononye SN, et al. (2012) The furan route to tropolones: probing the antiproliferative effects of β-thujaplicin analogs. Organic & Biomolecular Chemistry. 10: 8597-604 |