Jeffrey A. Chao, Ph.D.

Affiliations: 
2005 Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
structural role of RNA
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James R. Williamson grad student 2005 Scripps Institute
 (Molecular basis of RNA -protein recognition: Studies of yeast ribosomal protein L30e and Flock House virus B2.)
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Hochstoeger T, Papasaikas P, Piskadlo E, et al. (2024) Distinct roles of LARP1 and 4EBP1/2 in regulating translation and stability of 5'TOP mRNAs. Science Advances. 10: eadi7830
Ngo LH, Bert AG, Dredge BK, et al. (2024) Nuclear export of circular RNA. Nature
Eichenberger BT, Griesbach E, Mitchell J, et al. (2023) Following the Birth, Life, and Death of mRNAs in Single Cells. Annual Review of Cell and Developmental Biology. 39: 253-275
Hochstoeger T, Chao JA. (2023) Towards a molecular understanding of the 5'TOP motif in regulating translation of ribosomal mRNAs. Seminars in Cell & Developmental Biology
Dave P, Roth G, Griesbach E, et al. (2023) Single-molecule imaging reveals translation-dependent destabilization of mRNAs. Molecular Cell
Piskadlo E, Eichenberger BT, Giorgetti L, et al. (2022) Design, Labeling, and Application of Probes for RNA smFISH. Methods in Molecular Biology (Clifton, N.J.). 2537: 173-183
Gómez-Puerta S, Ferrero R, Hochstoeger T, et al. (2022) Live imaging of the co-translational recruitment of XBP1 mRNA to the ER and its processing by diffuse, non-polarized IRE1α. Elife. 11
Zinnall U, Milek M, Minia I, et al. (2022) HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins. Nature Communications. 13: 2727
Duchon A, Santos S, Chen J, et al. (2021) Plasma Membrane Anchoring and Gag:Gag Multimerization on Viral RNA Are Critical Properties of HIV-1 Gag Required To Mediate Efficient Genome Packaging. Mbio. e0325421
Mitchell J, Chao JA. (2021) Single-molecule mRNA and translation imaging in neurons. Biochemical Society Transactions
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