Daniela Fera, Ph.D.

Affiliations: 
2012 Chemistry University of Pennsylvania, Philadelphia, PA, United States 
Area:
Biological Chemistry
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"Daniela Fera"
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Ronen Marmorstein grad student 2012 Penn
 (Identification and characterization of small molecule antagonists of the human papillomavirus oncoproteins.)
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Publications

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Nguyen D, Lin LY, Zhou JO, et al. (2020) Identification and Characterization of a B-Raf Kinase α-Helix Critical for the Activity of MEK Kinase in MAPK Signaling. Biochemistry
Fera D, Lee MS, Wiehe K, et al. (2018) HIV envelope V3 region mimic embodies key features of a broadly neutralizing antibody lineage epitope. Nature Communications. 9: 1111
Williams WB, Zhang J, Jiang C, et al. (2017) Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations. Nature Communications. 8: 1732
Bonsignori M, Kreider EF, Fera D, et al. (2017) Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies. Science Translational Medicine. 9
Easterhoff D, Moody MA, Fera D, et al. (2017) Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial. Plos Pathogens. 13: e1006182
Bradley T, Fera D, Bhiman J, et al. (2015) Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site. Cell Reports
Fera D, Schmidt AG, Haynes BF, et al. (2014) Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains. Proceedings of the National Academy of Sciences of the United States of America. 111: 10275-80
Malecka KA, Fera D, Schultz DC, et al. (2014) Identification and characterization of small molecule human papillomavirus E6 inhibitors. Acs Chemical Biology. 9: 1603-12
Fera D, Marmorstein R. (2012) Different regions of the HPV-E7 and Ad-E1A viral oncoproteins bind competitively but through distinct mechanisms to the CH1 transactivation domain of p300. Biochemistry. 51: 9524-34
Fera D, Schultz DC, Hodawadekar S, et al. (2012) Identification and characterization of small molecule antagonists of pRb inactivation by viral oncoproteins. Chemistry & Biology. 19: 518-28
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