Sara J. Buhrlage, Ph.D.
Affiliations: | 2015 | Harvard Medical School/Dana-Farber Cancer Institute, Boston, MA, United States |
Area:
Chemical biologyGoogle:
"Sara Buhrlage"Mean distance: 8.57 | S | N | B | C | P |
Parents
Sign in to add mentorAnna K. Mapp | grad student | 2008 | University of Michigan | |
(Small molecule transcriptional activation domains.) | ||||
Nathanael Gray | research scientist | 2010-2015 | Harvard Medical School/Dana-Farber Cancer Institute |
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Publications
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Munshi M, Liu X, Kofides A, et al. (2022) A new role for the SRC family kinase HCK as a driver of SYK activation in MYD88 mutated lymphomas. Blood Advances |
Yang J, Weisberg EL, Qi S, et al. (2022) Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2. Leukemia |
Yang J, Weisberg EL, Liu X, et al. (2021) Small molecule inhibition of deubiquitinating enzyme JOSD1 as a novel targeted therapy for leukemias with mutant JAK2. Leukemia |
Yang G, Wang J, Tan L, et al. (2021) The HCK/BTK inhibitor KIN-8194 is active in MYD88 driven lymphomas and overcomes mutated BTKCys481 ibrutinib resistance. Blood |
Koduri V, Duplaquet L, Lampson BL, et al. (2021) Targeting oncoproteins with a positive selection assay for protein degraders. Science Advances. 7 |
Donovan KA, Ferguson FM, Bushman JW, et al. (2020) Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development. Cell |
Hatcher JM, Yang G, Wang L, et al. (2020) Discovery of a Selective, Covalent IRAK1 Inhibitor with Antiproliferative Activity in MYD88 Mutated B-Cell Lymphoma. Acs Medicinal Chemistry Letters. 11: 2238-2243 |
Weisberg E, Parent A, Yang PL, et al. (2020) Repurposing of Kinase Inhibitors for Treatment of COVID-19. Pharmaceutical Research. 37: 167 |
Schauer NJ, Liu X, Magin RS, et al. (2020) Selective USP7 inhibition elicits cancer cell killing through a p53-dependent mechanism. Scientific Reports. 10: 5324 |
Weisberg E, Meng C, Case A, et al. (2020) Correction: Evaluation of ERK as a therapeutic target in acute myelogenous leukemia. Leukemia |